Study of Nevisense Go Device Use at Home to Detect Early Atopic Dermatitis Flares in Adolescents and Adults

What this Trial Is About

Researchers are studying atopic dermatitis AD, a skin condition marked by worsening periods called flares. This observational study aims to evaluate an investigational device called Nevisense Go, which measures electrical properties of the skin related to its barrier function, to see if it can detect early changes that may predict AD flares before visible signs or symptoms appear. Participants aged 12 to 89 years with a history of AD flares are included. Participants will use the Nevisense Go device at home for about 90 days to take skin measurements five days a week. Along with these device measurements, they will complete electronic symptom diaries and attend up to five in-person study visits. The study collects data from both affected and unaffected skin areas, but device measurements will not affect clinical care or treatment decisions during the trial. During the study, researchers will assess the relationship between skin measurements and subsequent AD flares, develop and validate an algorithm to predict flare onset, and evaluate adherence and feasibility of device use. Participants will also complete patient- and clinician-reported measures of AD severity, itch, flare frequency, and flare resolution. The total participation lasts about 90 days, with ongoing data collection and evaluations to better understand flare prediction.

Evaluation of a Non-Invasive Device for Early Detection of Atopic Dermatitis Flares