Pupillometer-based objective chromatic perimetry in normal eyes and patients with retinal photoreceptor dystrophies.
Alon Skaat, Ifat Sher, Andrew Kolker...
https://pubmed.ncbi.nlm.nih.gov/23482470Actively Recruiting
Led by Sheba Medical Center · Updated on 2024-04-25
200
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are evaluating the use of objective perimetry with a chromatic multifocal pupillometer to monitor visual field defects in patients with retinal dystrophy and glaucoma. The study aims to assess the pupil light reflex (PLR) response to short and long wavelength light stimuli, comparing these measures between affected patients and healthy participants. This observational study focuses on improving the accuracy of detecting visual field defects using an advanced, computerized infrared video pupillometer. The pupillometer measures changes in pupil diameter in response to 76 small spot stimuli across a 30-degree visual field. The stimuli consist of short- and long-wavelength lights with peaks at 485 nm and 620 nm, respectively, presented at varying intensities and durations. The study includes three groups: healthy subjects as controls, patients with glaucoma, and patients with retinal dystrophy. The PLR responses are recorded during a single visit. Participants are involved in one visit where their pupil responses to light stimuli are measured. Assessments include recording the amplitude and latency of the PLR to evaluate differences in pupil reflex between healthy individuals and those with eye conditions. Researchers also monitor participant safety by excluding those with conditions that affect pupil measurement accuracy. Study participation ranges from 18 to 80 years of age, and participants provide informed consent before joining.
CONDITIONS
Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single visit
Participants undergo pupil light reflex measurement using a chromatic multifocal pupillometer to assess responses to short and long wavelength light stimuli at multiple points in the visual field.
1 visit (in-person)
Total: 1 location
1
Sheba Medical Center
Tel Litwinsky, Israel, 52621
Actively Recruiting
Y
Ygal Rotenstreich, MD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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Alon Skaat, Ifat Sher, Andrew Kolker...
https://pubmed.ncbi.nlm.nih.gov/23482470