Actively Recruiting

Age: 6Months - 17Years
All Genders
ID05915078

Evaluation of Clinical and Health Economic Outcomes Following In-office Tympanostomy Using the Tula4 System: a Prospective, Multi-center Registry

Led by Smith & Nephew, Inc. · Updated on 2024-07-23

200

Participants Needed

6

Research Sites

117 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are collecting real-world data on children aged 6 months to 17 years undergoing an in-office ear tube placement procedure called tympanostomy using the Tula4 System. This prospective, single-arm, multicenter registry aims to evaluate the outcomes and experiences associated with this FDA-approved system, which has been previously studied for safety and tolerability in pediatric patients. The study is sponsored by Smith & Nephew, Inc. and involves up to 20 centers across the US. The Tula System includes two main components: the Tula Iontophoresis System, which delivers the TYMBION12 otic anesthetic to numb the ear drum, and the Tula Tube Delivery System, which is used to place the ear tubes. Patients will receive their treatment during a single in-office visit, and no comparison groups are included since this is an observational registry. The procedure is performed following the System Instructions For Use, and patients are treated as part of standard medical care. Participants will be monitored with outcome data collected up to six months following the extrusion or removal of their tubes. Assessments include procedure success, tolerability and recovery reported by physicians and parents on the day of the procedure, anesthesia effectiveness, tube retention after one month, and various measures of parent satisfaction. This follow-up helps researchers understand the real-world performance and patient experience with the Tula System over time.

CONDITIONS

Brief Title

Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry

Who Can Participate

Age: 6Months - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients ages 6 months through 17 years of age (inclusive) at time of tympanostomy in-office using the Tula4 System
  • Patients who are candidates for in-office tube placement using the Tula System according to the System Instructions For Use
Not Eligible

You will not qualify if you...

  • Patients who are wards are not included

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Implementation

Duration - Day of procedure (day 0)

Participants undergo in-office tympanostomy using the Tula® System, including iontophoretic delivery of anesthetic and tube placement.

1 visit (in-person)

Post-operative Follow-up

Duration - 1 month post-procedure

Participants are monitored for tube retention and parent satisfaction following the procedure.

1 follow-up visit (in-person)

Trial Site Locations

Total: 6 locations

1

Advanced ENT and Allergy

Louisville, Kentucky, United States, 40220

Actively Recruiting

2

Regional Otolaryngology Head and Neck Associates

Cherry Hill, New Jersey, United States, 08034

Actively Recruiting

3

Rutgers Robert Wood Johnson Medical School

New Brunswick, New Jersey, United States, 08901

Actively Recruiting

4

Columbia University Vagelos College of Physicians and Surgeons

New York, New York, United States, 10032

Actively Recruiting

5

Ogden Clinic - Professional Center North

Ogden, Utah, United States, 84403

Actively Recruiting

6

Peak Pediatric Ear, Nose and Throat

Provo, Utah, United States, 84604

Actively Recruiting

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Research Team

C

Catherine E Whittall, BsC, Ph.D

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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