Actively Recruiting
Evaluation of the Patellar LIFT System for Subjects With Patellofemoral Cartilage Degeneration
Led by ZKR Orthopedics Inc · Updated on 2025-12-11
245
Participants Needed
5
Research Sites
375 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The PELICAN study is a prospective, non randomized, dual arm, multi-center clinical study comparing clinical outcomes of subjects treated with the LIFT Implant System to subjects treated with Tibial Tubercle Osteotomy (TTO).
CONDITIONS
Official Title
Evaluation of the Patellar LIFT System for Subjects With Patellofemoral Cartilage Degeneration
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients age 22 to 65 years at time of screening
- Anterior knee pain due to patellofemoral cartilage degeneration with a Modified Outerbridge score of 653 as assessed by MRI
- Body Mass Index (BMI) of 64 35
- Weight less than 300 lbs
- Anterior Knee Pain Score (AKPS) of 64 70 on a 0-100 scale
- Visual Analog Score (VAS) of 65 40 on a 0-100 scale
- Failure of at least 6 months of non-surgical treatment including rest, bracing, physical therapy, targeted exercise, NSAIDs, activity reduction, or modification
You will not qualify if you...
- Patellofemoral cartilage degeneration with a Modified Outerbridge Score of 2 or less at the study knee
- Clinical symptoms in the opposite knee that prevent daily activities, stair climbing or require assistive devices
- History of patella dislocation or instability
- Patella alta or patella baja
- Known tibial tubercle-trochlear groove (TT-TG) distance greater than 20mm
- Need for simultaneous cartilage grafting, transplantation, or bone marrow stimulation
- Previous repair of a torn patellar tendon
- Prior tibial tubercle osteotomy or knee joint replacement on the study knee
- Joint modifying surgery in the study knee within 6 months before planned procedure
- Arthroscopic surgeries in the study knee within 3 months before planned procedure
- Active infection, sepsis, osteomyelitis, or history of septic arthritis in any joint
- Rheumatoid arthritis, other inflammatory joint diseases, or autoimmune disorders
- History of avascular necrosis of any bone
- History of symptomatic patellar tendonitis or intrasubstance tear
- Insufficient cruciate or collateral ligaments or tendon instability preventing LIFT System use
- Pathologic ligament injury or meniscus tearing
- Clinical symptoms in the femoral-tibial joint of the study knee that prevent daily activities, stair climbing or require assistive devices
- Evidence of Grade 4 degenerative arthritis in the femoral-tibial joint explaining symptoms
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Horizon Clinical Research
La Mesa, California, United States, 91942
Actively Recruiting
2
Hospital for Special Surgery
New York, New York, United States, 10021
Actively Recruiting
3
NYU Langone Health
New York, New York, United States, 11220
Actively Recruiting
4
Ohio State University - Jameson Crane Sports Medicine Institute
Columbus, Ohio, United States, 43202
Actively Recruiting
5
Oregon Health and Science University
Portland, Oregon, United States, 97239
Actively Recruiting
Research Team
S
Sharon Branch
CONTACT
J
Jeff Halbrecht, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here