Collection of Data and Samples From People With Liver Disease and Healthy Volunteers to Study Liver Conditions and Genetic Influences

What this Trial Is About

Researchers are investigating acute and chronic liver diseases through a long-term observational study. The study aims to understand various liver diseases including hepatitis B, C, D, and E, primary biliary cirrhosis, Wilsons disease, hemochromatosis, nonalcoholic steatohepatitis, and others. It also explores genetic factors that might influence disease development, progression, and treatment outcomes. Participants include both patients with liver disease and healthy volunteers. Initial evaluations involve routine outpatient check-ups with blood and urine collection, liver ultrasounds, and possibly additional tests like liver or skin biopsies. Genetic samples are collected to support research on hereditary influences. Participants will be asked to return annually for follow-up visits. Throughout the study, participants undergo assessments including laboratory tests, imaging, and questionnaires. Researchers monitor disease susceptibility, progression, and response to treatment annually. Subjects eligible for experimental therapies may be offered such treatments. The study collects various biological samples and data over extended follow-up to support future liver disease research.

Evaluation of Patients With Liver Disease