Actively Recruiting
Evaluation of Patients With Non-obstructive Coronary Arteries
Led by Stanford University · Updated on 2025-06-05
2000
Participants Needed
1
Research Sites
2087 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patients with angina and non-obstructive CAD are common within clinical practice, but remain a challenge with regard to diagnosis and treatment. When these patients undergo a comprehensive evaluation at the time of invasive coronary angiography, occult coronary abnormalities are frequently found. We hope to learn the overall prevalence and presentation of these occult coronary abnormalities and its long term outcome in this patient population.
CONDITIONS
Official Title
Evaluation of Patients With Non-obstructive Coronary Arteries
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient referred for elective coronary angiography because of a reasonable clinical suspicion of coronary ischemia
- Presence of angina or an anginal equivalent including chest, back, shoulder, arm, neck, jaw discomfort, or shortness of breath brought on by physical exertion, emotional stress, or certain times of day or month
You will not qualify if you...
- Asymptomatic patients such as those undergoing pre-operative catheterization
- History of heart transplant
- Age under 18 years
- Renal insufficiency with creatinine greater than 1.5
- Presence of acute coronary syndrome (STEMI or NSTEMI), Tako-tsubo cardiomyopathy, abnormal ejection fraction under 55%, cardiogenic shock, or recent ventricular tachycardia/fibrillation
- Other likely explanations for chest pain such as pulmonary hypertension or aortic stenosis
- History of adverse reaction to medications used in the study (acetylcholine, nitroglycerin, adenosine, or heparin)
- Currently taking vasoactive medication such as nitroglycerin
- Inability to provide informed consent, including inability to speak, read, or understand English, Spanish, Chinese, Farsi, Japanese, Korean, Russian, or Vietnamese
- Hearing impairment preventing verbal conversation or visual impairment preventing reading consent
- Participation in another study except the Stanford Gene-PAD study
- Potentially vulnerable subjects including minors, pregnant women, economically or educationally disadvantaged, decisionally impaired, or homeless individuals
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Stanford University School of Medicine
Stanford, California, United States, 94305
Actively Recruiting
Research Team
V
Vedant Pargaonkar, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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