Study of Patients With Chest Pain and No Blockage in Heart Arteries Understanding Causes and Long-Term Outcomes of Angina Without Obstructive Coronary Artery Disease

What this Trial Is About

Researchers are studying patients who experience chest pain or discomfort and breathlessness but do not have blockages in their heart arteries, a condition called angina or ischemia with non-obstructive coronary arteries ANOCAINOCA. This registry aims to understand how common these conditions are, their causes, and the best ways to diagnose them, as well as to track long-term health outcomes in this group. Participants will undergo detailed heart evaluations as part of their standard care, including coronary angiography, intravascular ultrasound, and various tests of coronary artery function such as endothelial and microvascular assessments. Data from these procedures, along with tests for myocardial bridging and other coronary abnormalities, will be collected and entered into a research database. During the study, participants may be contacted periodically by phone or email for surveys and updates on their health status at 6 months, 1 year, 3 years, 5 years, 10 years, and every 5 years thereafter. Researchers will monitor outcomes including major cardiovascular events and changes in angina symptoms over up to 15 years. This long-term follow-up will help identify specific types of ANOCA and factors linked to cardiovascular risks.

Evaluation of Patients With Non-obstructive Coronary Arteries