Studying Different Placental Blood Transfusion Methods in Premature Babies to Prevent Complications and Impact Blood Health

What this Trial Is About

Researchers are evaluating different methods of placental transfusion in premature newborns to understand their effects on early life outcomes and blood health. The study focuses on premature infants born at or before 32 weeks gestational age, assessing how various transfusion techniques may influence their first days of life and overall prognosis. The trial compares three procedures intact umbilical cord milking, where the cord is milked toward the baby several times before clamping cut umbilical cord milking, involving clamping and cutting a long cord segment and milking the blood into the baby and delayed cord clamping, where the cord is clamped after a 30- to 60-second delay with the baby placed below placenta level. A control group will not receive any placental transfusion method. Participants will be admitted to the neonatal intensive care unit within their first day of life. Researchers will measure hemoglobin levels at admission and at the end of the first, second, and third weeks of life to assess blood health. The study is randomized and open-label, with no masking. The total participation period includes monitoring through the first three weeks after birth to evaluate the effects of the transfusion methods on premature infants hematological profiles and related complications.

Evaluation of Placental Transfusion Techniques in Prevention of Prematurity Related Complications and Effect on Their Hematological Profile