Actively Recruiting

Age: 18Years +
All Genders
NCT06895213

Evaluation of Plasma Renin Concentrations in Cardiac Surgery

Led by Mayo Clinic · Updated on 2026-05-13

100

Participants Needed

1

Research Sites

63 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this research is to learn more about how renin (a blood test) is affected by cardiopulmonary bypass, the heart-lung machine used during open heart surgery. Renin is a protein that may be elevated in response to low blood pressure or situations where organs do not receive sufficient oxygen. Renin may potentially be used as an indicator for specific treatments aimed to increase the blood pressure. This study will evaluate blood samples for renin concentration throughout the course of open heart surgery.

CONDITIONS

Official Title

Evaluation of Plasma Renin Concentrations in Cardiac Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult persons 18 years of age or greater.
  • Scheduled for an elective cardiac surgical procedure involving the use of cardiopulmonary bypass.
Not Eligible

You will not qualify if you...

  • Surgery involving heart or lung transplantation or implant of a durable left ventricular assist device.
  • Emergency cardiac surgery.
  • Established diagnosis of any congenital heart disease.
  • End-stage kidney disease receiving kidney replacement therapy before surgery.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Mayo Clinic

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

P

Patrick M Wieruszewski, Pharm.D.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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