Multicenter study of Platelet-Rich Plasma PRP treatment for chronic tendinopathies including patellar, Achilles, epicondylar, and plantar fasciitis

What this Trial Is About

Researchers are conducting a multicenter, prospective, observational study to evaluate the effectiveness and safety of Platelet-Rich Plasma PRP treatment for four types of tendinopathies patellar, Achilles, epicondylar, and plantar fasciosis. The study uses real-world evidence and data collected through the BioSmartData4 platform, including hematology analyzers for detailed PRP characterization, clinical variables, treatment protocols, and ongoing assessment of treatment response. Participants with chronic tendinopathy will receive PRP treatment following standardized protocols documented across centers. Variables such as the type of PRP leukocyte-rich or leukocyte-poor, preparation method single or double centrifugation, injected volume, anatomical site, administration technique preferably ultrasound-guided, number of treatment sessions, and intervals between sessions will be recorded. The study groups include patients treated for patellar tendinopathy, Achilles tendinopathy, plantar fasciosis, and chronic epicondylitis. During the 12-month follow-up, participants will undergo evaluations including pain scales like the Visual Analog Scale and condition-specific disability scores such as VISA-P, VISA-A, Patient Rated Tennis Elbow Evaluation Scale, and Foot Function Index at multiple time points. Researchers will also monitor predictive factors for treatment response and any adverse events. Participants treatment and progression will be observed in real-world clinical settings from baseline through one year after treatment.

Evaluation of Platelet-Rich Plasma (PRP) Treatment in Tendinopathies