Study of Portal Vein Stenting in Adults With Gastrointestinal Cancer and Portal Vein Narrowing Assessing Safety, Effectiveness, and Quality of Life

What this Trial Is About

Researchers are evaluating the safety and effects of portal vein stenting in patients with gastrointestinal cancers who have portal vein stenosis. The study aims to learn how long the portal vein remains open and free from blockage after stenting, and to assess the impact of the procedure on patients overall quality of life. It is an observational study involving two patient groups based on whether they receive the stenting procedure. One group, Cohort A, consists of patients who undergo portal vein stenting and complete quality of life questionnaires at 2-4 weeks and 6-8 weeks after the procedure. Medical records for these patients are also reviewed. Cohort B includes patients with portal vein thrombosis or stenosis who did not receive stenting, and their medical records are reviewed retrospectively for comparison. The study collects data on clinical success duration, liver volumes, nutritional status, laboratory values, and bleeding risk. Participants in Cohort A complete quality of life assessments and have their medical records reviewed up to 8 weeks following stent placement. Researchers measure outcomes such as stent patency, transfusion rates, need for procedures to remove fluid paracentesis, changes in liver function and volume, nutritional status, bleeding risk, and overall quality of life. Cohort B participants medical records are reviewed to compare these outcomes. The study duration extends through April 2028 with ongoing data collection from medical records and questionnaires.

Evaluation of Portal Vein Stenting in Patients With Portal Vein Stenosis and Gastrointestinal Cancers