Actively Recruiting

Age: 18Years +
All Genders
NCT04629677

Evaluation of Portal Vein Stenting in Patients With Portal Vein Stenosis and Gastrointestinal Cancers

Led by M.D. Anderson Cancer Center · Updated on 2026-01-12

150

Participants Needed

1

Research Sites

369 weeks

Total Duration

On this page

Sponsors

M

M.D. Anderson Cancer Center

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study collects information about the safety and effect of portal vein stenting in gastrointestinal cancer patients with portal vein stenosis. This study may help researchers learn how long the portal vein stays open and free from blockage and the effects of portal vein stenting on patients' overall well-being.

CONDITIONS

Official Title

Evaluation of Portal Vein Stenting in Patients With Portal Vein Stenosis and Gastrointestinal Cancers

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • COHORT A: Patients with gastrointestinal cancer undergoing standard staging and treatment
  • COHORT A: Patients with more than 75% narrowing of the main portal vein, left or right portal vein, or superior mesenteric vein
  • COHORT A: Patients with any narrowing and symptoms of portal hypertension such as variceal bleeding, refractory ascites, abdominal pain, intestinal swelling, or diarrhea after tumor causes are excluded
  • COHORT B: Patients with thrombosis or narrowing of the main portal vein who did not have portal vein stenting
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

M D Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

J

Joshua D. Kuban

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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