Actively Recruiting

Phase Not Applicable
Age: 65Years +
FEMALE
Healthy Volunteers
NCT07208916

Evaluation of the Potential of Grape Consumption to Improve Muscle Strength and Cognitive Function

Led by Western New England University · Updated on 2025-10-06

35

Participants Needed

1

Research Sites

33 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn if eating grapes can improve muscle strength and thinking in generally healthy women over 65. The main questions it aims to answer are: Does eating grapes improve muscle strength in women over 65? Does eating grapes improve cognition in women over 65? Participants will be asked to take part in 4 sessions on campus. Each session will include: Functional muscle strength testing Cognitive testing Blood draws

CONDITIONS

Official Title

Evaluation of the Potential of Grape Consumption to Improve Muscle Strength and Cognitive Function

Who Can Participate

Age: 65Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy female confirmed by medical history
  • Aged 65 or older
  • Able to walk household distances without assistance
  • Non-smoker
  • Dominant hand grip strength at or below normal for age and gender
  • No recreational drug use for one week prior to study
  • Agree not to participate in other clinical or patch test studies during this study
  • Completed medical intake
  • Read, understood, and signed informed consent
Not Eligible

You will not qualify if you...

  • Use of nasally inhaled, systemic, or topical corticosteroids within 4 weeks prior or during study
  • Use of systemic or topical antihistamines within 72 hours prior or during study
  • Use of certain antifungal drugs, antihistamines (including diphenhydramine), antibiotics (including sulfa drugs, quinolones, tetracyclines), oral diabetes drugs, sulfonylureas, diuretics, and tricyclic antidepressants
  • Use of some herbal supplements such as St. John's Wort
  • Unwillingness to refrain from acetaminophen (except occasional use, not within 48 hours of visits) or anti-inflammatory analgesics (aspirin, Aleve, Motrin, Advil, Orudis, Nuprin) within 72 hours prior and during study visits
  • Major surgery within 4 weeks prior to study start
  • Cytotoxic chemotherapy within 4 weeks prior to study
  • Hormonal therapy for cancer prevention within 4 weeks prior
  • Use of medications interfering with study results as judged by investigator
  • Known allergy or sensitivity to grape powder
  • Nut allergies
  • Treatment for any internal cancer within 5 years prior to study
  • History or current treatment for hepatitis, diabetes including insulin use, solid organ or bone marrow transplant, keloid formation, chronic renal or hepatic disorder, significant bleeding disorder, progressive neurodegenerative condition, or swallowing disorder
  • Any condition compromising study results
  • Uncontrolled illness including ongoing infection, symptomatic congestive heart failure, unstable angina, uncontrolled symptomatic cardiac arrhythmia, psychiatric illness, or social situations limiting compliance
  • Current participation in any clinical testing
  • Received investigational drugs within 28 days prior to Day 1

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Western New England University

Springfield, Massachusetts, United States, 01119

Actively Recruiting

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Research Team

B

Brittany C Adams

CONTACT

M

Michael V Salemi

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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