Actively Recruiting
Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr
Led by Weill Medical College of Cornell University · Updated on 2026-05-04
200
Participants Needed
4
Research Sites
248 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will be assessing the ability of PSMA-PET CT to determine the absence of clinically significant prostate cancer in patients on active surveillance (AS) with low risk and favorable intermediate-risk prostate cancer.
CONDITIONS
Official Title
Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male aged 18 years or older
- Histologically confirmed low or favorable intermediate risk prostate cancer per NCCN guidelines (Grade Group 2 must have 20% or less involvement in each core and no cribiform or intraductal carcinoma)
- PSA less than 20 ng/ml
- Ability to undergo yearly PSMA-PET CT
- Ability to undergo yearly prostate multiparametric MRI
- Ability to undergo transrectal or transperineal template and fusion prostate biopsy
- Willingness to have yearly prostate biopsies
You will not qualify if you...
- Prior treatment for prostate cancer
- Prior systemic therapy for prostate cancer
- Inability to undergo transrectal ultrasound
- Life expectancy less than 10 years
- Not interested in pursuing active surveillance
- Initial prostate cancer diagnosis more than 15 months ago
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
UCLA
Los Angeles, California, United States, 90005
Not Yet Recruiting
2
UCSF
San Francisco, California, United States, 94143
Not Yet Recruiting
3
Weill Cornell Medicine - New York Presbyterian Hospital
New York, New York, United States, 10065
Actively Recruiting
4
UH Cleveland Medical Center
Cleveland, Ohio, United States, 44106
Actively Recruiting
Research Team
H
Holly Kuczynski
CONTACT
S
Sarah Yuan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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