Actively Recruiting

Phase Not Applicable
Age: 18Years - 85Years
All Genders
Healthy Volunteers
NCT06363604

Evaluation of PWI Assisted by Marshall Ethanolization in Ablation of Persistent Atrial Fibrillation

Led by Xinhua Hospital, Shanghai Jiao Tong University School of Medicine · Updated on 2024-04-12

260

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, randomized controlled, single-blind, multi-center clinical trial study aiming to investigate whether the strategy of posterior wall isolation (PWI) assisted by vein of Marshall ethanol infusion (VOMEI) could improve the success rate of persistent atrial fibrillation ablation.

CONDITIONS

Official Title

Evaluation of PWI Assisted by Marshall Ethanolization in Ablation of Persistent Atrial Fibrillation

Who Can Participate

Age: 18Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Between 18 and 85 years old
  • Symptomatic, non-valvular persistent atrial fibrillation lasting at least 1 week
  • Refractory to at least one antiarrhythmic drug
  • Prepared to undergo atrial fibrillation catheter ablation
  • Provide informed consent and agree to follow-up evaluations
Not Eligible

You will not qualify if you...

  • Acute myocardial infarction within the last 3 months
  • Acute heart failure or new cerebral infarction within 3 months
  • On the heart transplant list
  • Life expectancy less than 1 year
  • Untreatable bleeding disorders
  • Presence of left atrial thrombus
  • Heart failure with NYHA class III-IV or ejection fraction below 40%
  • Uncontrolled malignant tumor
  • Significant liver or kidney dysfunction (ALT, AST more than twice normal or creatinine clearance below 50%)
  • Previous catheter ablation or cardiac surgery for atrial fibrillation
  • Women who are pregnant, breastfeeding, planning pregnancy, or of childbearing age not using reliable contraception

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Xinhua Hospital, Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, China, 200092

Actively Recruiting

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Research Team

Y

Yichi YU, Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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