Actively Recruiting
Prospective Evaluation of Quality of Life and Utilities Following Surgical Treatment of Rectal Cancer
Led by M.D. Anderson Cancer Center · Updated on 2026-04-06
430
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
Researchers are evaluating quality of life and health state utilities in patients with stage I-IV rectal cancer who have undergone surgical treatment. The study aims to understand how treatment affects patients' well-being over time and to compare the impact of treatments with or without (neo)adjuvant radiation therapy. This observational study may help improve knowledge about living with or after rectal cancer. Participants complete quality of life questionnaires at several time points: before surgery, at 6 and 12 months after surgery, and then annually at 2, 3, 4, and 5 years post-surgery. These repeated assessments help capture changes in quality of life and health status over an extended period. The study is sponsored by M.D. Anderson Cancer Center and involves no interventional treatments. During the study, participants will spend about 20 to 30 minutes completing questionnaires at each visit. Researchers analyze these responses to measure health state utilities and quality of life changes over time, focusing especially on data collected at 24 months after surgery. This long-term follow-up provides valuable insight into patient experiences after rectal cancer surgery, with the overall participation lasting up to five years.
CONDITIONS
Brief Title
Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient has histologically proven adenocarcinoma of the rectum (stage I - IV) planned for surgical resection with curative intent or has already received surgical treatment
- Patient must sign an approved informed consent document
- Patient must have the literacy and physical ability to complete questionnaires in English
You will not qualify if you...
- Patient has been treated with pelvic radiation therapy for a diagnosis other than rectal cancer
- Patient has a concurrent cancer diagnosis at the time of consent
- Patient has recurrent disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote) for consent and eligibility assessment
Duration - Baseline to 5 years post-surgery
Participants have undergone surgical treatment for rectal cancer and are assessed post-surgery.
Questionnaire visits at baseline, 6 and 12 months, and 2, 3, 4, and 5 years after surgery
Duration - Up to 5 years post-surgery
Participants complete quality of life questionnaires to monitor health state utilities and quality of life over time.
Questionnaire assessments at 2, 3, 4, and 5 years after surgery
Trial Site Locations
Total: 1 location
1
M D Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
G
George Chang
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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