Transrectal ultrasound and the diagnosis of rectovaginal endometriosis: a prospective observational study.
Anthony Griffiths, Roxani Koutsouridou, Sue Vaughan...
https://pubmed.ncbi.nlm.nih.gov/18382872/Actively Recruiting
Led by Başakşehir Çam & Sakura City Hospital · Updated on 2025-01-15
15
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are evaluating intraoperative transrectal ultrasound TRUS to measure how deeply and extensively bowel tissue is affected in women with deep infiltrative endometriosis DIE involving the intestine. This study focuses on patients diagnosed before surgery using transvaginal ultrasound and MRI and who are scheduled for bowel resection. The goal is to assess how well TRUS compares to MRI in identifying the diseases extent. The study involves 15 to 40 female participants aged 18 to 55 who have bowel involvement due to DIE and require bowel resection. Before surgery, participants will undergo pelvic exams, imaging tests including transvaginal ultrasound and MRI, and pain assessments using a visual analog scale. During surgery, TRUS will be performed to measure the depth and length of rectal involvement, and these findings will be compared to the preoperative MRI results to evaluate TRUSs diagnostic accuracy. Participants will be closely monitored from enrollment through 16 months, with data collected on demographics, patient characteristics, pain levels, and surgical details. The main outcome is how TRUS measurements during surgery match with MRI findings before surgery. The study is conducted at specialized hospitals with a team of gynecologists, radiologists, and surgeons working together to analyze the results and improve understanding of bowel involvement in DIE.
CONDITIONS
Evaluation of Rectal Infiltration Depth and Length in Bowel Involvement of Deep Infiltrative Endometriosis (DIE) Using Intraoperative Transrectal Ultrasound (TRUS)
B
Baris Kaya, Associate Professor
S
Sercan Yuksel, Associate Professor
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Başakşehir Çam & Sakura City Hospital
Lead Sponsor
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Preoperative evaluations include pelvic examination, imaging (transvaginal ultrasound and MRI), and pain assessment using a visual analog scale (VAS).
Duration - Day of surgery
Participants undergo intraoperative transrectal ultrasound (TRUS) during bowel resection surgery to measure the depth and length of rectal involvement due to deep infiltrative endometriosis.
1 intraoperative visit during bowel resection surgery
Duration - Up to 16 months
Participants are followed for up to 16 months to compare intraoperative ultrasound findings with preoperative MRI and assess demographic, pain, and surgical outcomes.
Follow-up visits as per surgical and clinical care schedules
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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Lead Sponsor