Evaluation of Rectal Infiltration Depth and Length in Bowel Involvement of Deep Infiltrative Endometriosis Using Intraoperative Transrectal Ultrasound

What this Trial Is About

Researchers are evaluating the use of intraoperative transrectal ultrasound (TRUS) to measure the depth and length of bowel involvement in women with deep infiltrating endometriosis (DIE) who have been diagnosed preoperatively with intestinal endometriosis. The goal is to compare TRUS measurements taken during surgery with preoperative MRI results to assess its effectiveness in this setting. The study focuses on female patients aged 18 to 55 who require bowel resection due to DIE. This is a prospective, single-arm study involving 15 to 40 female participants. Before surgery, patients will undergo pelvic exams, transvaginal ultrasound (TVUS), MRI imaging, and pain assessments using a visual analog scale (VAS). During the bowel resection surgery, TRUS will be performed to measure rectal infiltration depth and length. The TRUS results will then be compared to the MRI findings using statistical methods including sensitivity, specificity, and ROC curve analysis. Participants will be closely monitored from enrollment through 16 months. Evaluations include imaging studies, clinical exams, and pain assessments. The main outcome measure is comparing intraoperative TRUS with preoperative MRI to determine accuracy in assessing rectal involvement. The study is conducted at Istanbul Başakşehir Çam and Sakura City Hospital with teams from gynecology, radiology, and general surgery collaborating.

Evaluation of Rectal Infiltration Depth and Length in Bowel Involvement of Deep Infiltrative Endometriosis (DIE) Using Intraoperative Transrectal Ultrasound (TRUS)