Actively Recruiting
Evaluation of the Relevance of Antithrombin Prescriptions at Strasbourg University Hospitals
Led by University Hospital, Strasbourg, France · Updated on 2025-12-10
160
Participants Needed
1
Research Sites
54 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Antithrombin (AT) is a physiological inhibitor of the coagulation cascade. In therapeutics, its presence in sufficient quantities is necessary for the pharmacological activity of unfractionated heparin (UFH) and partially low-molecular-weight heparin (LMWH). In intensive care, patients are mostly treated with anticoagulants for either preventive or curative purposes, particularly for those whose care requires renal replacement therapy (RRT), extracorporeal membrane oxygenation (ECMO), or cardiopulmonary bypass (CPB). The use of various types of membranes associated with these procedures can lead to degradation of blood proteins (including AT). An imbalance in hemostasis can then occur, resulting in ineffective anticoagulation. At the Strasbourg University Hospitals (HUS), these medications are directly available in the intensive care units, allowing for immediate administration in an emergency. Pharmaceutical and medical analysis is therefore not performed before administration.
CONDITIONS
Official Title
Evaluation of the Relevance of Antithrombin Prescriptions at Strasbourg University Hospitals
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult subject (≥18 years old)
- Female and male
- Having received antithrombin during the study period, in intensive care or operating room during the period from January 1, 2022 to December 31, 2023.
You will not qualify if you...
- Subject (and/or their legal representative, if applicable) having expressed their opposition to the reuse of their data for scientific research purposes
- Minor subject
AI-Screening
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Trial Site Locations
Total: 1 location
1
Service d'Anesthésie et Réanimation chirurgicale - CHU de Strasbourg - France
Strasbourg, France
Actively Recruiting
Research Team
X
Xavier DELABRANCHE, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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