Actively Recruiting
Evaluation of the Relevance of Diaphragmatic Stroke Ultrasound for the Etiological Diagnosis of Acute Respiratory Distress in an Emergency Department.
Led by University Hospital, Montpellier · Updated on 2024-12-06
100
Participants Needed
2
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this Prospective interventional multicenter diagnostic study is to investigate the use of diaphragmatic ultrasound (DE) as a diagnostic tool in an adult emergency department for patients in acute respiratory distress. The main question it aims to answer is to evaluate the relevance of measuring the Sum of Plateau Times (SPT) by Clinical Ultrasound in Emergency Medicine (CHEM) for the diagnosis of pneumopathy during acute respiratory distress (ARD) in the Emergency Department. Secondary objectives include the study of other diaphragmatic ultrasound parameters, inspiratory plateau time (IPT) and expiratory plateau time (EPT), and the diagnostic relevance of PTS for the diagnosis of decompensation of Chronic obstructive pulmonary disease (BPCO) and acute cardiogenic pulmonary edema (APO). Each eligible patient will have a right diaphragmatic ultrasound performed by a trained physician, then clinicobiological data will be collected later from medical records, and the etiological diagnosis will be established by a committee of 2 experts in the management of respiratory distress.
CONDITIONS
Official Title
Evaluation of the Relevance of Diaphragmatic Stroke Ultrasound for the Etiological Diagnosis of Acute Respiratory Distress in an Emergency Department.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 18 years of age or older
- Patients with acute respiratory distress defined by a respiratory rate over 25 breaths per minute and/or signs of breathing difficulty such as thoraco-abdominal rocking, active abdominal breathing, or use of extra-diaphragmatic respiratory muscles
- Peripheral oxygen saturation (SpO2) below 90% and/or hypercapnic acidosis with pH below 7.35 and pCO2 above 45mmHg on arterial blood gases
- Patients breathing spontaneously without mechanical ventilation
- Patients with clinical severity scores of Grade 1 with signs of struggle, Grade 2, or Grade 3, based on respiratory rate ranges from 20 to 50 breaths per minute
You will not qualify if you...
- Adults under legal protection such as guardianship or curatorship
- Refusal to give consent after being informed about the study
- Patients on non-invasive ventilation
- Patients on mechanical ventilation
- Respiratory rate higher than 50 breaths per minute
- Patients currently treated with antibiotics for infectious pneumopathy
- Pregnant or breastfeeding women
- Patients with known diaphragmatic diseases
- Individuals who are illiterate or unable to understand the study purpose and methods
- Patients not affiliated with or covered by a social security scheme
- Persons deprived of liberty by judicial or administrative decision or forced hospitalization
- Participants currently involved in another study with an ongoing exclusion period
AI-Screening
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Trial Site Locations
Total: 2 locations
1
University Hospital of Nîmes
Nîmes, Gard, France, 30900
Not Yet Recruiting
2
University Hospital of Montpellier
Montpellier, Hérault, France, 34295
Actively Recruiting
Research Team
D
DINO TIKVESA, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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