Study of Diaphragmatic Ultrasound to Diagnose Causes of Acute Respiratory Distress in Adults at Emergency Departments
Led by University Hospital, Montpellier · Updated on 2024-12-06
100
Participants Needed
2
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the use of diaphragmatic ultrasound as a diagnostic tool in adult emergency departments for patients experiencing acute respiratory distress ARD. The study aims to evaluate the usefulness of measuring the Sum of Plateau Times SPT with Clinical Ultrasound in Emergency Medicine to diagnose pneumopathy during ARD. Secondary goals include assessing other ultrasound parameters like inspiratory and expiratory plateau times and their role in diagnosing COPD exacerbation and acute cardiogenic pulmonary edema.
Participants aged 18 and older who come to the emergency department with ARD will receive a right diaphragmatic ultrasound performed by trained doctors using a specialized cardiac probe. The examination involves the patient sitting at a 45-degree angle while spontaneous breathing occurs. The ultrasound captures six respiratory cycles to measure specific diaphragmatic movement times. Clinical and biological data will be collected later to confirm diagnoses by expert reviewers.
During the study, participants will undergo the diaphragmatic ultrasound exam and have their medical records reviewed for clinical and laboratory information. Researchers will analyze ultrasound measurements like SPT to determine their accuracy in diagnosing pneumopathy and other conditions causing respiratory distress. The study will monitor specificity, sensitivity, predictive values, and likelihood ratios related to these ultrasound parameters. Participation involves one diagnostic procedure and follow-up assessments based on medical record review, with no intervention beyond standard care.
CONDITIONS
Brief Title
Evaluation of the Relevance of Diaphragmatic Stroke Ultrasound for the Etiological Diagnosis of Acute Respiratory Distress in an Emergency Department.
Research Team
D
DINO TIKVESA, MD
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Acute respiratory distress defined by respiratory rate above 25 and/or signs of breathing difficulty such as thoraco-abdominal rocking or active abdominal breathing
Peripheral oxygen saturation below 90% and/or hypercapnic acidosis (pH below 7.35 and pCO2 above 45mmHg) on arterial blood gases
Spontaneous breathing without mechanical ventilation
Clinical severity score Grade 1 with signs of struggle or Grades 2 and 3 severity
You will not qualify if you...
Adults under legal protection or guardianship
Refusal to consent
Use of non-invasive or mechanical ventilation
Respiratory rate above 50 breaths per minute
Current antibiotic treatment for infectious pneumopathy
Pregnant or breastfeeding women
History of diaphragmatic diseases
Illiteracy or inability to understand study purpose
Not affiliated with a social security scheme
Legal or administrative deprivation of liberty
Participation in another study with overlapping exclusion period
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Single assessment at presentation
Participants undergo diaphragmatic ultrasound to assist in diagnosing the cause of acute respiratory distress in the emergency department.
1 visit (in-person)
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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Published Research Related To This Trial
ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC.
John J V McMurray, Stamatis Adamopoulos, Stefan D Anker...
Management of acute exacerbations of chronic obstructive pulmonary disease (COPD). Guidelines from the Société de pneumologie de langue française (summary).