Study of Right Heart Function Measured by Echocardiography to Predict Success of Breathing Support Removal in ICU Adults

What this Trial Is About

This research aims to evaluate whether right ventricular function measured by transthoracic echocardiography TTE can predict successful weaning from mechanical ventilation in adult ICU patients. The study focuses on assessing the predictive value of TAPSE Tricuspid Annular Plane Systolic Excursion and other right heart parameters such as tricuspid S velocity, right ventricular fractional area change RV-FAC, right atrial area, and pulmonary valve acceleration time for extubation outcomes. It is a prospective observational study conducted in a single center. Participants are adult ICU patients who are mechanically ventilated and planned for weaning. They will undergo a single bedside TTE within two hours after meeting clinical weaning criteria and being hemodynamically stable. Echocardiographic measurements of right heart function will be taken as part of routine care prior to extubation. No experimental treatments are administered during the study. During the study, participants will be monitored for 24 hours after extubation to assess if they successfully maintain spontaneous breathing without needing reintubation, non-invasive ventilation, or high-flow oxygen support. Data collected will include echocardiographic parameters, clinical and demographic information, blood gas analysis, and vital signs. The primary outcome is the ability of TAPSE to predict weaning success. Secondary outcomes involve other echocardiographic variables and their correlation with extubation results. The total participation involves the echocardiography assessment and the 24-hour follow-up period.

Evaluation of Right Ventricular Function to Predict Weaning Success in the Intensive Care Unit