Actively Recruiting

Phase Not Applicable
Age: 5Years - 18Years
All Genders
NCT04935918

EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENCE THERAPY BALLOONS IN BLADDER EXSTROPHY AND INCONTINENT EPISPADIAS PATIENTS

Led by Assistance Publique Hopitaux De Marseille · Updated on 2021-06-23

7

Participants Needed

1

Research Sites

363 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to evaluate the effectiveness and safety of a minimally invasive surgical procedure with ACT (Adjustable Continence Therapy) balloons implantation for the treatment of urinary incontinence in children with bladder exstrophy or isolated epispadias. The ACT therapy consists of two small adjustable silicone balloons connected with a tubing to a port, surgically placed around the bladder neck, one on each side of the urethra.

CONDITIONS

Official Title

EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENCE THERAPY BALLOONS IN BLADDER EXSTROPHY AND INCONTINENT EPISPADIAS PATIENTS

Who Can Participate

Age: 5Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Boys and girls older than 5 years with bladder exstrophy or isolated epispadias
  • Sphincteric urinary incontinence with leak point pressure less than 45 cm H2O
  • Open bladder neck during filling and stress urinary incontinence
  • Normal kidney function with eGFR greater than 90 ml/min
  • No or stable upper urinary tract dilatation on ultrasound
Not Eligible

You will not qualify if you...

  • Younger than 5 years or older than 18 years
  • Acute or chronic kidney failure
  • Progressive deterioration of the upper urinary tract such as hydronephrosis
  • Uncontrolled detrusor instability
  • Residual urine volume greater than 100 ml after urination
  • Bleeding disorders

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Assistance Publique Hopitaux de Marseille

Marseille, PACA, France, 13354

Actively Recruiting

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Research Team

A

Alice FAURE, MD

CONTACT

C

Claire MORANDO

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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EVALUATION OF THE SAFETY AND EFFICACY OF ADJUSTABLE CONTINENCE THERAPY BALLOONS IN BLADDER EXSTROPHY AND INCONTINENT EPISPADIAS PATIENTS | DecenTrialz