Actively Recruiting

Phase Not Applicable
Age: 50Years - 85Years
All Genders
NCT07319377

Evaluation of Safety and Efficacy of a Digital Therapeutic Device to Improve Strength in Sarcopenia (Sarc-DTx)

Led by Exosystems · Updated on 2026-05-12

130

Participants Needed

2

Research Sites

43 weeks

Total Duration

On this page

Sponsors

E

Exosystems

Lead Sponsor

T

The Catholic University of Korea

Collaborating Sponsor

AI-Summary

What this Trial Is About

This clinical trial aims to demonstrate that the use of a digital therapeutic device (exoDTx) in patients with sarcopenia is superior to self-exercise in terms of muscle strength improvement and safety.

CONDITIONS

Official Title

Evaluation of Safety and Efficacy of a Digital Therapeutic Device to Improve Strength in Sarcopenia (Sarc-DTx)

Who Can Participate

Age: 50Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of sarcopenia according to both EWGSOP and 2019 AWGS criteria
  • Reduced muscle strength: handgrip < 28 kg for men or < 18 kg for women, or five-times sit-to-stand test time > 12 seconds without arm support
  • Reduced muscle mass: skeletal muscle mass index < 7.0 kg/m² for men or < 5.4 kg/m² for women by DXA, or < 7.0 kg/m² for men or < 5.7 kg/m² for women by BIA
  • Ability to perform sit-to-stand movements independently
  • Sufficient physical and cognitive ability to take part in the exercise program
  • Ability to provide written informed consent
  • Ability to operate a mobile phone independently or with caregiver assistance
Not Eligible

You will not qualify if you...

  • Cognitive impairment with Mini-Mental State Examination score < 20 or inability to participate due to cognitive decline
  • Presence of an implanted cardiac pacemaker
  • Uncontrolled cardiovascular disease despite treatment
  • Lower limb surgery within the past 6 months causing inability to walk independently
  • Moderate to severe musculoskeletal pain or limitations affecting functional assessments
  • Severe obesity with body mass index > 50 kg/m²
  • Active cancer treatment or severe systemic frailty
  • Hemiplegia causing inability to perform the exercise program
  • Anticipated inability to complete the study protocol
  • Inability to follow study instructions delivered in Korean

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Bucheon St. Mary's Hospital

Bucheon-si, South Korea

Actively Recruiting

2

St.Vincent's hospital

Suwon, South Korea

Actively Recruiting

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Research Team

S

Sangui Choi, CPO

CONTACT

E

Eun Ji Lee, AP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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