What this Trial Is About

Researchers are evaluating sarcopenia, a condition involving loss of muscle mass and strength, in women at different life stages, including menopausal women who are and are not receiving hormone replacement therapy (HRT), as well as pre-menopausal women. The study aims to compare muscle strength and mass outcomes among these groups to understand the effects of HRT and menopausal status. This observational study includes women aged 18 to 65 attending a gynecology clinic. Participants will be divided into three groups: menopausal women taking HRT, menopausal women not taking HRT, and pre-menopausal women not using hormonal products. Various tests will be used to assess muscle strength and mass, including the SARC-F questionnaire, handgrip test, chair stand test, and bioimpedance measurement. These methods evaluate physical function and estimate lean muscle mass safely and easily. During their visit, participants will undergo a physical exam, blood pressure measurement, gynecological exam, and blood and urine tests. Researchers will also collect health history information such as diet, exercise, smoking, medications, and prior surgeries. Outcomes will focus on strength and muscle mass changes over one year. Data will be gathered through clinical records and direct testing, with an estimated 180 women expected to participate.

Evaluation of Sarcopenia in Women in Different Stages of Life and in Hormonal Therapy or Not