Actively Recruiting
Evaluation of the Severity of Hepatic Fibrosis by Magnetic Resonance Elastography in the Diagnosis of Endogenous Hypercorticism
Led by Central Hospital, Nancy, France · Updated on 2023-10-25
21
Participants Needed
1
Research Sites
148 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The main hypothesis of the HEPACORT study is that upon diagnosis of endogenous Cushing's syndrome, significant liver fibrosis may be present, particularly in the most severe forms of Cushing's syndrome. the HEPACORT study is the first exploratory study to assess the severity of liver fibrosis in patients with Cushing's syndrome or suspected of presenting by Magnetic Resonance Elastography (MRE).
CONDITIONS
Official Title
Evaluation of the Severity of Hepatic Fibrosis by Magnetic Resonance Elastography in the Diagnosis of Endogenous Hypercorticism
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Affiliated with or beneficiary of a social security scheme
- Received complete information about the study and signed informed consent
- Completed a preliminary clinical examination suitable for the research
- Diagnosed with Cushing's syndrome (Cushing's Syndrome group)
- Suspected of having Cushing's syndrome based on a dexamethasone suppression test with plasma cortisol between 18 and 50 µg/L within the last 3 months (suspected Cushing's Syndrome group)
- Diagnosed with metabolic syndrome (metabolic syndrome group)
You will not qualify if you...
- Received corticosteroid therapy for more than 3 months during the 2 years before inclusion
- Received corticosteroid therapy shorter than 3 months with discontinuation less than one month before inclusion
- Taken anticortisolic treatment for more than 3 months during the 2 years before inclusion
- Have chronic liver disease
- Have alcohol misuse defined as consuming more than 10 standard units weekly
- Have a body type that prevents MRI examination
- Woman of childbearing age without effective contraception
- Have contraindication to MRI examination
- Persons referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the French Public Health Code
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CHRU Nancy
Nancy, France
Actively Recruiting
Research Team
N
Nicolas SCHEYER, MD
CONTACT
G
Guillaume DROUOT, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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