Actively Recruiting

Phase 4
All Genders
NCT07533110

Evaluation Of The Success Rate of NOVAMag® SHIELD

Led by Egas Moniz - Cooperativa de Ensino Superior, CRL · Updated on 2026-04-21

40

Participants Needed

1

Research Sites

80 weeks

Total Duration

On this page

Sponsors

E

Egas Moniz - Cooperativa de Ensino Superior, CRL

Lead Sponsor

B

Botiss Biomaterials GmbH

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study hypothesizes that the SHIELD technique, when combined with a suitable bone graft material, enables successful immediate implant placement in Type 3 extraction sockets with buccal bone dehiscence, regardless of the extent of buccal bone loss. Specifically, it is proposed that the regenerative potential of the SHIELD technique is not significantly affected by the degree of buccal bone dehiscence, whether in compromised sockets (ST3 Subclass B, when a buccal dehiscence is present and extending 1/3 to 2/3 of the total length of the alveolus) or severely compromised sockets (ST3 Subclass C, for severe dehiscence passing more than 2/3 of the facial bone of the alveolus). All in all, this study aims to assess the clinical performance of the CE-approved medical device NOVAMag® SHIELD by evaluating its success rate and long-term suitability for the rehabilitation of edentulous regions in routine clinical settings. It further seeks to generate clinically meaningful evidence supporting the safety and efficacy of magnesium-based biomaterials in the management of complex post-extraction defects. In addition, the study investigates the CE-approved self-tapping conical implant VEGA® + to obtain comprehensive clinical data contributing to post-market surveillance and continuous product evaluation.

CONDITIONS

Official Title

Evaluation Of The Success Rate of NOVAMag® SHIELD

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older;
  • Willingness and ability to provide informed consent and accept participation in the study.
  • Presence of a tooth indicated for extraction in the aesthetic zone (including premolars);
  • Clinical indication for immediate implant placement following tooth extraction;
  • Extraction sockets classified as Socket Type 3 (ST3), Subclass B or C, according to the Steigmann (2022) classification;
Not Eligible

You will not qualify if you...

  • Pregnancy or lactating women;
  • Systemic diseases or conditions known to affect bone metabolism (osteoporosis, uncontrolled diabetes, metabolic bone disorders, chronic corticosteroid therapy, etc.);
  • Active infection at the surgical site, including the presence of an acute abscess or other signs of ongoing local infection;
  • Hypersensitivity to the biomaterials intended for use in the regenerative procedure.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Clinica Dentaria Egas Moniz

Almada, Setúbal District, Portugal, 2829-511

Actively Recruiting

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Research Team

P

Patrícia Lyra, PhD

CONTACT

J

João Botelho, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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