Actively Recruiting
Evaluation of SUMMIT BRUSH in Treatment of Blepharitis
Led by University of Notre Dame · Updated on 2020-11-27
60
Participants Needed
3
Research Sites
103 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Dry Eye Disease (DED) is a multifactorial disease that affects \~15-30 million people in the USA alone. It creates an enormous societal and economic burden, decreases productivity in the workplace, and affects the quality of lives of the people affected by this disease. DED is primarily caused by blepharitis, a chronic inflammation of the eyelid margins. If left untreated, blepharitis results in the obstruction and loss of the glands responsible for tear film production. The standard of care is the use of self-administered at home commercially available products, e.g., eyelid foams, gels, and pads. Although these products are helpful, they have limitations. Patients often require expensive in office procedures, e.g., lid debridement with exfoliation devices or more expensive procedures. The scope of this project is to evaluate the effectiveness of a new self-administered disposable ocular brush used in conjunction with the most common eyelid cleanser. The investigators are looking to see if combining the microexfoliation provided by the brush with the eyelid cleanser is more effective at removing the eyelid debris than the cleanser alone.
CONDITIONS
Official Title
Evaluation of SUMMIT BRUSH in Treatment of Blepharitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical signs and symptoms of blepharitis (Staphylococcal and Demodex)
- Visible collarettes, clear sleeves, and scurfs on eyelid margins seen with Slit Lamp Biomicroscopy
- Age 18 years or older
You will not qualify if you...
- Active hordeolum (stye)
- Chalazion
- Periorbital cellulitis
- Allergic eyelid dermatitis
- Acute bacterial conjunctivitis
- Open periorbital wounds
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
University of Colorado
Boulder, Colorado, United States, 80303
Actively Recruiting
2
Michiana Eye Center
Mishawaka, Indiana, United States, 46545
Actively Recruiting
3
Kentucky Eye Institute
Lexington, Kentucky, United States, 40509
Actively Recruiting
Research Team
G
Giles E Duffield, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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