Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07404787

SAFEGUARD Phase 2 Pathfinding Study to Prevent Suicide Among Soldiers Discharged From Psychiatric Hospitalization

Led by Uniformed Services University of the Health Sciences · Updated on 2026-03-25

1500

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

Sponsors

U

Uniformed Services University of the Health Sciences

Lead Sponsor

H

Harvard Medical School (HMS and HSDM)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the effectiveness of Pathfinding, a 6-month telehealth case management program, to reduce suicidal behaviors among active-duty Regular Army soldiers recently discharged from inpatient psychiatric treatment. This study focuses on soldiers across the U.S. transitioning back to the community, comparing the Pathfinding intervention plus Treatment As Usual (TAU) versus TAU alone. The goal is to determine if Pathfinding lowers suicide-related behaviors and to identify which soldiers benefit most from it. The Pathfinding intervention is delivered remotely by trained mental health professionals called "Guides" and integrates two evidence-based case management programs tailored for active-duty soldiers. It includes initial sessions focused on orientation, support person involvement, goal setting, and resource identification, followed by brief monitoring contacts over 6 months. Participants may involve a support person during some sessions. The comparison group receives the Army's standard post-discharge care, which includes discharge planning, risk assessment, and follow-up appointments. Participants complete a baseline assessment soon after discharge, followed by follow-up assessments at 6 and 12 months to report suicide-related events and other outcomes. Researchers will also review participants' electronic healthcare and Army administrative data during these periods. The primary outcome is suicide-related behaviors within 12 months after baseline. Secondary outcomes include suicide attempts, rehospitalization, non-suicide death, risky behaviors, suicide ideation, and psychological resilience. The study monitors safety and progress through electronic health record documentation throughout.

CONDITIONS

Brief Title

Evaluation of a Telehealth Case Management Intervention to Prevent Suicide Among Soldiers Discharged From Psychiatric Hospitalization

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Active duty Regular Army soldiers recently discharged from inpatient psychiatric care at a military treatment facility in the US
  • Access to telephone and computer (including smartphone)
Not Eligible

You will not qualify if you...

  • Impaired ability to provide informed consent
  • Terminal illness
  • Failure to complete baseline survey within 30 days of discharge
  • Positive screen for post-discharge suicide-related behaviors

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit

Treatment

Duration - 6 months

Participants receive either the Pathfinding telehealth case management intervention in addition to standard post-discharge care or Treatment As Usual (TAU) alone. The Pathfinding intervention involves remote sessions with trained Guides focusing on suicide risk factors and unmet needs over 6 months. TAU involves standard discharge planning, risk assessment, and follow-up care.

Initial 4 sessions soon after discharge, followed by up to 10 brief remote contacts; TAU includes weekly or biweekly follow-up visits depending on clinical need

Follow-up

Duration - Up to 12 months post baseline

Participants complete follow-up assessments at 6 and 12 months after baseline to track suicide-related behaviors and other health outcomes.

2 follow-up assessments (6 and 12 months post baseline)

Trial Site Locations

Total: 1 location

1

Uniformed Services University of the Health Sciences

Bethesda, Maryland, United States, 20814

Actively Recruiting

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Research Team

P

Pathfinding Study

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Published Research Related To This Trial

Design of a multicenter randomized controlled trial of a post-discharge suicide prevention intervention for high-risk psychiatric inpatients: The Veterans Coordinated Community Care Study.

Lauren M Weinstock, Todd M Bishop, Mark S Bauer...

https://pubmed.ncbi.nlm.nih.gov/39352173

Predicting suicides after psychiatric hospitalization in US Army soldiers: the Army Study To Assess Risk and rEsilience in Servicemembers (Army STARRS).

Ronald C Kessler, Christopher H Warner, Christopher Ivany...

https://pubmed.ncbi.nlm.nih.gov/25390793

Evaluation of a Model to Target High-risk Psychiatric Inpatients for an Intensive Postdischarge Suicide Prevention Intervention.

Ronald C Kessler, Mark S Bauer, Todd M Bishop...

https://pubmed.ncbi.nlm.nih.gov/36652267