Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06686472

Evaluation of TL-925 for the Treatment of Allergic Conjunctivitis

Led by Telios Pharma, Inc. · Updated on 2024-11-13

66

Participants Needed

1

Research Sites

9 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this prospective, Phase 2, randomized, double-masked, vehicle controlled study, approximately 66 eligible subjects will be randomized 1:1 to receive either TL-925 or placebo as topical ophthalmic eye drops administered bilaterally. The study comprises of a screening and treatment period using the conjunctival allergen challenge model to evaluate TL-925 for the treatment of allergic conjunctivitis.

CONDITIONS

Official Title

Evaluation of TL-925 for the Treatment of Allergic Conjunctivitis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals aged 18 years or older
  • Female subjects of childbearing potential and their male partners must both use a highly effective contraception method during the study
  • Documented history of ocular allergies and a positive skin test to seasonal or perennial allergens within the past 60 months
  • Best-corrected visual acuity of 0.7 LogMAR or better
  • Positive bilateral conjunctival allergen challenge reaction
Not Eligible

You will not qualify if you...

  • Any systemic or ocular disease causing eye redness or discomfort or interfering with the study
  • Any eye surgery within the last 3 months or refractive surgery within the last 6 months
  • Any ongoing ocular infection (bacterial, viral, or fungal)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Telios Investigative Site

Memphis, Tennessee, United States, 38119

Actively Recruiting

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Research Team

J

John Mei

CONTACT

Y

Yulia Khalina

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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