Actively Recruiting
Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem
Led by Unilever R&D · Updated on 2026-04-30
150
Participants Needed
1
Research Sites
22 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective of this clinical study is to evaluate the impact on gingival health when participants switch to a fluoride toothpaste without gum-health actives for 4 weeks after using a proven gum-health toothpaste for 13 weeks.
CONDITIONS
Official Title
Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be able to understand the study and provide informed consent.
- Able to read and understand study instructions and documents.
- Have at least 20 natural teeth without subgingival calculus, including 5 assessable teeth in each quadrant (excluding 3rd molars).
- Have a mean whole mouth bleeding on probing (BOP) of 10% or more at screening.
- Willing to follow lifestyle and dietary restrictions during the study.
You will not qualify if you...
- Pregnant or breastfeeding women.
- Participation in a gum health study within 3 months before screening.
- Currently participating in other cosmetic, dental clinical studies, or trials.
- Use of any gum health products in the 4 weeks before screening.
- Untreated caries or significant periodontal disease affecting study validity or participant wellbeing.
- More than three sites with probing pocket depth (PPD) of 5 mm or greater.
- Wearing full or partial dentures.
- Undergoing orthodontic treatment.
- Current smokers or recent smoking history, including e-cigarettes.
- Diagnosed diabetes.
- Dental prophylaxis in the month before enrollment or scheduled before study end.
- Medical conditions or medication use affecting study outcomes as judged by the study dentist.
- Use of dietary supplements like multivitamins, antioxidants, or fish oils.
- Known allergy to any study product ingredients.
- Employment with Unilever or membership on the study team.
- Any other condition deemed by the investigator to exclude participation.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Faculty of Dentistry, University of Indonesia
Jakarta Pusat, Indonesia, 10430
Actively Recruiting
Research Team
A
Associate Prof. Benso Sulijaya
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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