Actively Recruiting
Evaluation and Treatment of Adhesive Capsulitis Using Non-invasive Neurostimulation Devices
Led by Université du Québec à Chicoutimi · Updated on 2025-01-28
30
Participants Needed
1
Research Sites
128 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this randomized controlled trial is to compare the integrity of somatosensory processing with transcranial magnetique stimulation (TMS) and corticospinal excitability of the affected shoulder in individuals with adhesive capsulitis versus healthy controls. The secondary objective is to compare the clinical and neurophysiological effects of an intervention using tendon vibration (VIB) to induced kinesthetic illusions. This will involve comparing two groups: one receiving a real intervention versus a placebo intervention protocol, both coupled with standardized exercises in individuals with capsulitis. The hypotheses are that the proprioceptive processing and corticospinal excitability are impaired in the presence of capsulitis, and that the VIB + exercises intervention will result in greater improvements than the placebo VIB + exercises. To goal is to establish the first empirical foundations for understanding adhesive capsulitis, using cutting-edge neurophysiological investigation technologies. TMS will be used to explore the presence of maladaptive plasticity in motor networks by assessing the excitability and integrity of the primary motor cortex (M1) and the corticospinal tract. Recruitement: 30 healthy participants and 30 participants with a diagnosis of adhesive capsulitis will undergo 2 baselines assesments, 6 interventions with tendon vibration and 2 follow-up evaluation. Participants will be age- and sex-matched. Baseline and follw-up include: * Questionnaires : SPADI, QuickDASH, French version of the Mcgill Pain Questionnaire; * Active and passive range of motion; * Ultrasound for diagnosing capsulitis. Comparison parameters: * active motor threshold (aMT) * Motor evoked potential (MEP) latency and amplitude * Standardized kinesthetic illusion procedure (SKIP) : direction of illusion, clearness, amplitude/speed. Interventions : * 2 baselines including all questionnaires, ultrasound, active and passive range of motion, TMS procedure and SKIP; * 2 VIB interventions per week, for 3 weeks * Real VIB : 80Hz of vibration to induce kinesthetic illusions, * Placebo VIB : 40Hz of vibration that does not induce kinesthetic illusions * 2 follow-up including all questionnaires, ultrasound, active and passive range of motion, TMS procedure and SKIP.
CONDITIONS
Official Title
Evaluation and Treatment of Adhesive Capsulitis Using Non-invasive Neurostimulation Devices
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years old and over
- Good general health
- Diagnosis of adhesive capsulitis (experimental group) or no shoulder pain (placebo group)
You will not qualify if you...
- Cognitive disorders
- Any neurological disease or injury affecting the upper limbs
- History or diagnosis of muscle, tendon, or capsular tear
- Shoulder surgery or prosthesis
- Pregnant women
- Presence of metal in the skull or jaw
- History of epilepsy
AI-Screening
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Trial Site Locations
Total: 1 location
1
Lab BioNR - UQAC
Saguenay, Quebec, Canada, G7H 2B1
Actively Recruiting
Research Team
É
Émilie Bouchard, M.Sc. PhD candidate
CONTACT
L
Louis-David Beaulieu, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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