Actively Recruiting

Age: 3Years +
All Genders
ID00001645

Evaluation, Treatment, and Monitoring of Patients With Known or Suspected Parasitic Infection

Led by National Institute of Allergy and Infectious Diseases (NIAID) · Updated on 2026-03-16

800

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating, treating, and monitoring patients who have known or suspected parasitic infections, including those with malaria, intestinal worms, GI protozoa, echinococcus, and strongyloides. This prospective observational study aims to understand diagnosis, treatment, and disease progression using standard medical practices without experimental treatments. The study is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID). Participants will be grouped based on the type of parasitic infection they have, such as GI parasites, echinococcus, intestinal worms, malaria, or other parasitic infections. Treatment plans are individualized according to each patient's condition and follow standard medical care. The number and length of clinic visits and diagnostic evaluations vary per patient and are determined by the study doctor. During the study, participants will undergo physical exams, medical history reviews, and routine lab tests including blood, stool, and urine samples. Blood draws will be limited to safe amounts based on age and weight. Additional tests may include x-rays, EKGs, or tissue biopsies if needed. Responses to treatment will be assessed at scheduled visits, with timing and total duration personalized to each patient's medical situation. The main outcome measured is the diagnosis, treatment, and understanding of parasitic infections over a one-year period.

CONDITIONS

Brief Title

Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection

Who Can Participate

Age: 3Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 3 or over
  • Access to a primary medical care provider outside of the NIH
  • Clinical evidence suggestive of a parasitic infection
Not Eligible

You will not qualify if you...

  • Less than 3 years of age
  • No evidence suggestive of a parasitic infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Varies depending on individual evaluation

Participants undergo medical history, physical examination, routine laboratory tests, and specialized diagnostic procedures to evaluate for parasitic infections.

Multiple visits depending on individual condition

Long-term Monitoring

Duration - Up to 1 year

Participants with known or suspected parasitic infections are monitored over time to evaluate treatment response and disease progression.

Follow-up visits scheduled based on individual treatment plans

Trial Site Locations

Total: 1 location

1

National Institutes of Health Clinical Center

Bethesda, Maryland, United States, 20892

Actively Recruiting

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Research Team

T

Thomas B Nutman, M.D.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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Published Research Related To This Trial

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Madelynn Corda, Joshua Sciurba, Jiana Blaha...

https://pubmed.ncbi.nlm.nih.gov/35617367