Human infection with Strongyloides stercoralis and other related Strongyloides species.
Thomas B Nutman
https://pubmed.ncbi.nlm.nih.gov/27181117Actively Recruiting
Led by National Institute of Allergy and Infectious Diseases (NIAID) · Updated on 2026-03-16
800
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are evaluating, treating, and monitoring patients who have known or suspected parasitic infections, including those with malaria, intestinal worms, GI protozoa, echinococcus, and strongyloides. This prospective observational study aims to understand diagnosis, treatment, and disease progression using standard medical practices without experimental treatments. The study is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID). Participants will be grouped based on the type of parasitic infection they have, such as GI parasites, echinococcus, intestinal worms, malaria, or other parasitic infections. Treatment plans are individualized according to each patient's condition and follow standard medical care. The number and length of clinic visits and diagnostic evaluations vary per patient and are determined by the study doctor. During the study, participants will undergo physical exams, medical history reviews, and routine lab tests including blood, stool, and urine samples. Blood draws will be limited to safe amounts based on age and weight. Additional tests may include x-rays, EKGs, or tissue biopsies if needed. Responses to treatment will be assessed at scheduled visits, with timing and total duration personalized to each patient's medical situation. The main outcome measured is the diagnosis, treatment, and understanding of parasitic infections over a one-year period.
CONDITIONS
Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Varies depending on individual evaluation
Participants undergo medical history, physical examination, routine laboratory tests, and specialized diagnostic procedures to evaluate for parasitic infections.
Multiple visits depending on individual condition
Duration - Up to 1 year
Participants with known or suspected parasitic infections are monitored over time to evaluate treatment response and disease progression.
Follow-up visits scheduled based on individual treatment plans
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
T
Thomas B Nutman, M.D.
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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