Actively Recruiting
Evaluation and Treatment of Neurosurgical Disorders
Led by National Institute of Neurological Disorders and Stroke (NINDS) · Updated on 2026-04-20
5000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Objective: This protocol is designed to allow evaluation of participants neurosurgical disorders that receive care within the Surgical Neurology Branch. The participants will receive standard-of-clinical-care evaluation and treatment. The clinical data and samples generated during standard of care treatment will be collected as a part of this study. Study Population: Participants 4 years of age and older with neurosurgical-related conditions seeking care from, or referred to the Surgical Neurology Branch for evaluation are eligible for this protocol. Study Design: This is an observational study. Participants will receive standard-of- clinical-care evaluation and treatment for their neurosurgical condition. Clinical evaluation may include laboratory and radiological studies designed to aid in diagnosis or differential diagnosis of the participant s condition or to facilitate treatment. The evaluations may take place in the outpatient clinic areas or in the inpatient units. Some participants will receive standard-of-care medical or surgical treatment for their disorder. Clinical data, tissue samples or body fluids obtained during standard of care treatment, may be used for research. Additional genetic testing may be performed on subjects and their blood relatives if a genetic mechanism underlying the neurological disorder is suspected. Patients in this study may choose to consent to skin biopsies for research purposes, in which case they will sign an additional consent document for thesethis research procedure. Outcome Measures: No additional research outcome measures will be tracked in this study, as this study is collecting data for potential future use. All outcomes will be those of standard clinical evaluation and treatment. A clinical and research database will be kept of patient s diagnosis, progression, and treatment. Clinical database information may be reported or be used in other studies.
CONDITIONS
Official Title
Evaluation and Treatment of Neurosurgical Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be age 4 and older.
- Participants must seek care from, or be referred to the Surgical Neurology Branch for evaluation and management of neurosurgical conditions such as central nervous system tumors, peripheral nerve tumors, epilepsy, Parkinson's disease, movement disorders, Chiari syndrome, central nervous system malformations, and pain disorders.
- Adults must be able to provide informed consent or have a legally authorized representative to provide consent if incapacitated.
- For minors, a parent or legal guardian must be able to provide consent.
- Blood relatives of subjects suspected to have a genetic neurological disorder may participate for genetic testing only.
- Participants must be willing to consent for collection of clinical data or biological samples or their cryopreservation (for those having skin biopsies and/or saliva samples).
You will not qualify if you...
- Patients who are unable to undergo evaluation and treatment for a neurosurgical disorder.
- Subjects without an established diagnosis of a well-characterized disease with validated treatment algorithms at the time of enrollment, if resource investment is not expected to advance knowledge (for those providing biological samples only).
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
S
Surgical Neurology Branch
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here