Circulating S100A8 and S100A9 protein levels in plasma of patients with acquired aplastic anemia and myelodysplastic syndromes.
Valentina Giudice, Zhijie Wu, Sachiko Kajigaya...
https://pubmed.ncbi.nlm.nih.gov/29958797Completed
Age: 2Years - 110Years
All Genders
ID00001397
Evaluation, Treatment and Training Protocol for Patients With Bone Marrow Failure States, Isolated or Multilineage Cytopenias, Metastatic Solid Tumors, or Hematologic Malignancies
Led by National Heart, Lung, and Blood Institute (NHLBI) · Updated on 2020-10-08
1452
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is designed to allow the evaluation, follow-up, and medical care of patients with blood disorders not currently participating in a research study being conducted by the Hematology Branch of the National Heart, Lung and Blood Institute (NHLBI) or not being screened for participation in a study. The purpose of this study is to allow investigation into the blood disorders of patients in order to teach, learn, and gather more information about diseases of the blood. In addition, this study allows researchers the opportunity to evaluate patients referred to the Hematology Branch of the NHLBI with rare or undiagnosed diseases of the blood. This may be potentially beneficial to the patient and at the same time contribute to the development of new research ideas.
CONDITIONS
Official Title
Evaluation, Treatment, and Training for Patients With Blood Disorders
Who Can Participate
Age: 2Years - 110Years
All Genders
Eligibility Criteria
You may qualify if you...
- INCLUSION CRITERIA:
Patients (and when appropriate the patient's stem cell donor) may be entered on this protocol at the discretion of the Principal and/or Associate Investigators if :
An investigator decides that it is in the best interest of the patient/donor and the Branch for the patient to be enrolled in this protocol while awaiting a decision on eligibility for other protocols; or after enrollment on another protocol, or to allow careful evaluation of patients with unique or rare disorders of direct interest to the Branch; or with more common disorders for fellowship teaching purposes.
The patient or the patient's guardian is capable of informed consent and signs the consent form. The consent form will be signed by parents or guardians of patients under the age of 18.
Age greater than or equal to 2 and weight greater than 12 kg.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
Status Unknown
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Published Research Related To This Trial
Circulating exosomal microRNAs in acquired aplastic anemia and myelodysplastic syndromes.
Valentina Giudice, Lauren G Banaszak, Fernanda Gutierrez-Rodrigues...
https://pubmed.ncbi.nlm.nih.gov/29674506Deep sequencing and flow cytometric characterization of expanded effector memory CD8+CD57+ T cells frequently reveals T-cell receptor Vβ oligoclonality and CDR3 homology in acquired aplastic anemia.
Valentina Giudice, Xingmin Feng, Zenghua Lin...
https://pubmed.ncbi.nlm.nih.gov/29419434