Actively Recruiting
Sarcoma Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography
Led by Mayo Clinic · Updated on 2026-02-06
50
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate how well intraoperative indocyanine green (ICG) dye and fluoroscopic technology can help confirm negative surgical margins during tumor removal for patients with bone or soft tissue sarcoma. The study is observational and focuses on comparing the accuracy of ICG fluorescence during surgery with the final pathology results to better guide tumor resection. Participants in this study receive an infusion of ICG dye before their scheduled tumor resection surgery. During the operation, the ICG fluorescence is used to guide the surgeon in identifying tumor margins. The study involves reviewing medical records and surgical outcomes without altering standard treatment plans. Participants will be involved during their surgery with ICG infusion and have their medical records reviewed afterward. Researchers will assess how accurately the ICG fluorescence matches the final pathology findings. The study tracks outcomes related to tumor margin confirmation and operates under standard clinical care procedures, with no additional treatment or follow-up beyond usual care.
CONDITIONS
Brief Title
Evaluation of Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography in Patients With Sarcoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with biopsy-proven bone or soft tissue sarcoma undergoing resection
- Age 18 years or older
You will not qualify if you...
- Age less than 18 years
- Chronic kidney disease
- History of anaphylaxis to dyes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Day of surgery
Participants receive an infusion of indocyanine green (ICG) prior to their scheduled sarcoma resection surgery and are monitored during the procedure.
1 visit (in-person)
Duration - Up to several weeks after surgery
Participants' medical records are reviewed after surgery to evaluate outcomes related to the ICG fluorescence guidance used during resection.
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
C
Clinical Trials Referral Office
L
Laura Dohrmann
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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