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An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample
Led by U.S. Army Medical Research and Development Command · Updated on 2025-01-23
950
Participants Needed
3
Research Sites
324 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Given the high prevalence of post-traumatic stress disorder (PTSD) in veterans and active duty military, the focus of this research study is to test the reliability of two new PTSD assessments, the Clinician Administered PTSD Scale for DSM-5 (CAPS-5) and the PTSD Symptom Scale Interview for DSM-5 (PSSI-5) and compare the results between the two new assessments and the previous "gold standard", the Clinician Administered PTSD Scale for DSM-IV (CAPS-IV). Biomarkers believed to be related to PTSD (e.g., biofluid biomarkers, cognitive and physiological markers, and neural activity as measured by EEG) will be collected to inform targeted interventions in specific groups of patients and other large-scale biomarker discovery efforts in the field. Participants will be 950 male and female active duty military and veterans ages 18 or older who have been exposed to at least one traumatic event.
CONDITIONS
Official Title
An Evaluation of Two PTSD Assessments in an Active Duty and Military Veteran Sample
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female active duty personnel or military veterans, 18 years of age or older
- Competent to give informed consent
- Have experienced any Criterion A qualifying traumatic event as defined by the Life Events Checklist for DSM-5 (LEC-5)
- Score a 3 or above on the Primary Care-Post Traumatic Stress Disorder Screen (PC-PTSD-5)
You will not qualify if you...
- Current suicidal or homicidal ideation with a plan
- Substance use disorder requiring detoxification currently or in the past month
- Assessment using CAPS or PSSI in the previous 1 year
- Currently receiving psychotherapy or counseling for PTSD
- Moderate to severe cognitive impairment as measured by the Montreal Cognitive Assessment (MoCA)
- Meet criteria for unmedicated Bipolar I, Bipolar II, Schizophrenia, or other psychotic disorders in the last month
AI-Screening
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Trial Site Locations
Total: 3 locations
1
Tripler Army Medical Center
Honolulu, Hawaii, United States, 96859
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2
Cincinnati VA Medical Center - Trauma Recovery Center
Fort Thomas, Kentucky, United States, 41075
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3
Walter Reed National Military Medical Center
Bethesda, Maryland, United States, 20814
Actively Recruiting
Research Team
S
Savannah Noppert
CONTACT
D
Derrell Anderson, MS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
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