Actively Recruiting

Age: 18Years +
All Genders
NCT04053855

Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma

Led by Centre Hospitalier Universitaire de Saint Etienne · Updated on 2026-05-06

100

Participants Needed

1

Research Sites

339 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Clear cell renal cell carcinoma is diagnosed by imaging, sometimes associated with biopsy. This diagnosis is expensive, invasive and sometimes late. The development of a simple biological test for diagnosis is essential. Exosomes are 30 to 150 nm membrane vesicles secreted into the extracellular space by various living cells. These exosomes can be isolated from biological fluids, including urine. The recent study of urinary exosomes is a promising topic for analyzing tumor markers in urine. The investigator's goal is to develop a reliable technique for detecting tumor exosomes in urine in patients with clear cell renal cell carcinoma. The analysis of urinary exosomes could provide a new liquid biopsy tool for the early diagnosis of clear cell renal cell carcinoma.

CONDITIONS

Official Title

Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a renal mass requiring surgery (partial or total nephrectomy)
  • Affiliated with social security
  • Signed informed consent
  • Unscheduled nephrectomy controls
  • Affiliated with social security
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Insufficient urine sample volume (less than 100 ml)
  • Use of a urinary catheter
  • Under court-ordered guardianship or curatorship

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chu Saint-Etienne

Saint-Etienne, France

Actively Recruiting

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Research Team

N

Nicolas MOTTET, MD PhD

CONTACT

A

Arnauld GARCIN, CRA

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma | DecenTrialz