Actively Recruiting
Evaluation of Uterine Fibroids by CEUS and SHAPE Pre and Post UAE
Led by Thomas Jefferson University · Updated on 2025-04-10
80
Participants Needed
1
Research Sites
87 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study goals are to determine the patterns of uterine fibroid vascularity pre and post UAE using CEUS resulting in an alternative to gadolinium-enhanced MRI that is less expensive, has less contra-indications and side effects, is real time, and noninvasive helping physicians to evaluate the result of UAE procedures. Also, this study will evaluate uterine fibroid pressures using SHAPE, comparing the results with normal myometrium tissue in order to determine its characteristics and tissue differences, which we believe will lead to the development of a new biomarker for the diagnosis and treatment of uterine fibroids.
CONDITIONS
Official Title
Evaluation of Uterine Fibroids by CEUS and SHAPE Pre and Post UAE
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be a female diagnosed with endometrial cancer and scheduled for UAE.
- Be over the age of 18 years.
- If of child-bearing potential, must have a negative pregnancy test.
- Be conscious and able to comply with study procedures.
- Have read and signed the IRB approved consent form for participating in the study.
You will not qualify if you...
- Females who are pregnant or nursing.
- Received an investigational drug in the 30 days before study drug administration or will receive one within 72 hours afterwards.
- Medically unstable, seriously or terminally ill, or with unpredictable clinical course.
- On life support or in a critical care unit.
- Clinically unstable cardiac arrhythmias such as recurrent ventricular tachycardia.
- Recent cerebral hemorrhage.
- Underwent surgery within 24 hours prior to the study sonographic examination.
- Congenital heart defects.
- Known allergy to Definity.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Thomas Jefferson University
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
Research Team
P
Priscilla Machado, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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