Actively Recruiting
Evaluation Viral RNA and Virus Infectivity in Exhaled Air Before and After Use of One Dose With ColdZyme Mouth Spray
Led by Lund University · Updated on 2026-04-06
200
Participants Needed
1
Research Sites
178 weeks
Total Duration
On this page
Sponsors
L
Lund University
Lead Sponsor
E
Enzymatica AB
Collaborating Sponsor
AI-Summary
What this Trial Is About
Many respiratory diseases spread through aerosols. ColdZyme is a mouth spray that protects against upper respiratory tract viruses causing common cold and flu-like symptoms. ColdZyme forms a protective moisturizing barrier on the mucous membrane of the oral cavity and throat. The objective of this study is assessing if ColdZyme could also contribute to decreased airborne transmission by decreasing the amount of (infectious) virus that is exhaled by an infected subject.
CONDITIONS
Official Title
Evaluation Viral RNA and Virus Infectivity in Exhaled Air Before and After Use of One Dose With ColdZyme Mouth Spray
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male and female subjects above age 18 (inclusive)
- Sudden onset of at least one symptom of upper respiratory tract infection such as cough, sore throat, shortness of breath, non-allergic rhinitis, fever or feverishness, malaise, headache, or myalgia
- Generally in good health as judged by the Investigator
- Willing and able to provide written informed consent for participation
You will not qualify if you...
- Known allergy or hypersensitivity to components of ColdZyme
- Use of immunosuppressive therapy within the last 4 weeks before Visit 1 or during the study
- Diagnosed chronic respiratory disease that may affect study results, as judged by the Investigator
- Unhealed wounds or mucosal lesions in the mouth or throat
- Participation in another clinical study within 30 days before Visit 1
- Active smokers
- Investigator considers the subject unlikely to follow study procedures and requirements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Lund University
Lund, Sweden, 22100
Actively Recruiting
Research Team
J
Jakob Löndahl, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here