Actively Recruiting

Age: 18Years +
All Genders
NCT05692726

Evaluation of Volume and Electrolyte Balance in Hyponatremia Treatment - a Prospective Observational Trial

Led by University of Cologne · Updated on 2025-09-11

50

Participants Needed

1

Research Sites

206 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To assess quantitatively the evolution over time of electrolyte-free water clearance and electrolyte mass balance in patients with non-hypervolemic hypotonic hyponatremia

CONDITIONS

Official Title

Evaluation of Volume and Electrolyte Balance in Hyponatremia Treatment - a Prospective Observational Trial

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients 18 years or older
  • Diagnosed with hypotonic hyponatremia
  • Glucose-corrected plasma sodium less than 130 mmol/l
  • Serum osmolality less than 280 mosmol/kg or no signs of non-hypotonic hyponatremia
Not Eligible

You will not qualify if you...

  • Signs of extracellular volume expansion
  • Liver cirrhosis with severe liver damage (AST/ALT greater than 3 times upper limit, AP greater than 6 times upper limit, Bilirubin 3 mg/dl or higher)
  • Heart failure
  • On dialysis or have oliguric renal impairment with plasma creatinine 3 mg/dl or higher
  • History of organ transplantation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital of Cologne

Cologne, Germany, 50937

Actively Recruiting

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Research Team

V

Volker Burst, MD, Prof

CONTACT

S

Sadrija Cukoski

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Evaluation of Volume and Electrolyte Balance in Hyponatremia Treatment - a Prospective Observational Trial | DecenTrialz