Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06469970

Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults

Led by Centre Hospitalier Régional Metz-Thionville · Updated on 2026-03-12

15

Participants Needed

1

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a prospective, observational, monocentric, phase II (exploratory) cohort study aiming to describe the evolutionary profile of the initial volume of glucose distribution (IDVG) during the first four days of management of severely burned patient.

CONDITIONS

Official Title

Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients over 18 years of age
  • Patients hospitalized with burns of at least 30% of body surface area
  • Burns caused by a thermal mechanism
  • Patients treated at the CHR Metz-Thionville burn center
  • Patients managed within 8 hours after the burn injury
  • Patient affiliated with a social security scheme
  • Written consent obtained from the patient or authorized representative, or emergency inclusion if consent cannot be obtained
Not Eligible

You will not qualify if you...

  • Diabetic patients on insulin
  • Patients with contraindications to Glucose 30% Proamp injection
  • Patients who had cardiac arrest before hospital arrival
  • Patients undergoing extracorporeal circulation (ECMO, ECLS) or continuous renal replacement therapy (CRRT)
  • Patients without a central venous line or arterial catheter
  • Moribund patients or those with immediate therapeutic limitations
  • Patients unable to undergo trans-pulmonary thermodilution monitoring due to vascular access issues
  • Pregnant, parturient, or breastfeeding women
  • Patients under guardianship, curatorship, or legal protection
  • Patients with cognitive impairments or language barriers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHR Metz-Thionville/Hopital de Mercy

Metz, France, 57085

Actively Recruiting

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Research Team

A

Arpiné EL NAR, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults | DecenTrialz