Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06415474

Evolution of the Lymphocyte Phenotype in Patients with Infection in Intensive Care Unit

Led by University Hospital, Brest · Updated on 2025-02-05

80

Participants Needed

1

Research Sites

108 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Patients admitted for polytrauma, severe neurological injury, post-operative monitoring or sepsis/septic shock present with significant inflammation, leading to immunoparalysis, which is responsible for infection, particularly prolonged infection. A study of their lymphocyte phenotype over time could help explore the phenomenon of immunoparalysis.

CONDITIONS

Official Title

Evolution of the Lymphocyte Phenotype in Patients with Infection in Intensive Care Unit

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Postoperative esophagectomy surveillance within the last 24 hours
  • Patients with intra-abdominal infection
  • Neurological patients with intubation planned for more than 24 hours (subarachnoid hemorrhage with coma, severe head trauma, ischemic or hemorrhagic stroke with coma)
  • Polytrauma with intubation planned for more than 24 hours
  • Patient aged 18 and over
  • Patient with social security coverage
Not Eligible

You will not qualify if you...

  • Hereditary immune deficiency HIV-AIDS
  • Malignant hemopathies
  • Immunosuppressive treatment other than corticosteroid therapy or chemotherapy
  • Patient under legal protection
  • Pregnant or breast-feeding women

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU de Brest

Brest, France, 29609

Actively Recruiting

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Research Team

E

Etienne BOTQUELEN, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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