Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05989152

Evolution of PET Fixation With FDG at the End of Antibiotic Treatment of Infective Endocarditis on Valvular Prosthesis

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-08-05

50

Participants Needed

1

Research Sites

136 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In patients with prosthetic valve endocarditis (PVE) and pathological valvular FDG uptake on the initial FDG-PET and not referred to valve replacement at the acute phase, the study will assess whether FDG-PET is able to identify those at increased risk of PVE relapse.

CONDITIONS

Official Title

Evolution of PET Fixation With FDG at the End of Antibiotic Treatment of Infective Endocarditis on Valvular Prosthesis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient aged 18 or over
  • Prosthetic valve implanted surgically or by catheter for at least 3 months
  • Definite infective endocarditis on a prosthetic valve according to ESC definition
  • FDG-PET scan for diagnosis showing pathological uptake on the prosthetic valve performed within 15 days after starting antibiotic therapy
  • No cardiac surgery performed or planned for the current infective episode before end-of-treatment FDG-PET
Not Eligible

You will not qualify if you...

  • Patient under legal protection, guardianship, or curatorship
  • Pregnancy or breastfeeding
  • Not affiliated with health insurance or social security scheme
  • Participating simultaneously in another FDG-PET study
  • No informed consent signed

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hôpital Bichat-Claude Bernard

Paris, France, France, 75018

Actively Recruiting

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Research Team

F

François Rouzet, MD, PHD

CONTACT

X

Xavier Duval, MD, PHD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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