Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07261891

Ex Vivo Evaluation of JAK-inhibitor and Gene Therapeutical Approach in JAK-STAT Related Disorders

Led by prof. dr. Rik Schrijvers · Updated on 2025-12-03

20

Participants Needed

1

Research Sites

314 weeks

Total Duration

On this page

Sponsors

P

prof. dr. Rik Schrijvers

Lead Sponsor

R

Research Foundation - Flanders (Fonds Wetenschappelijk Onderzoek)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators want to study the JAK-inhibitors and their impact on the immune system and evaluate the potential of a gene-therapeutic strategy

CONDITIONS

Official Title

Ex Vivo Evaluation of JAK-inhibitor and Gene Therapeutical Approach in JAK-STAT Related Disorders

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients with a genetically confirmed or highly suspected disorder causing overactivation of the JAK-STAT pathway
  • Healthy individuals without immune-mediated disease eligible as controls
Not Eligible

You will not qualify if you...

  • Children under 18 years at the time of recruitment
  • Individuals unable or unwilling to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospitals Leuven,

Leuven, Vlaams-Brabant, Belgium, 3000

Actively Recruiting

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Research Team

R

Rik Schrijvers, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Ex Vivo Evaluation of JAK-inhibitor and Gene Therapeutical Approach in JAK-STAT Related Disorders | DecenTrialz