Bloodstream Infection and Colorectal Cancer Risk in Queensland Australia, 2000-2019.
Kevin B Laupland, Felicity Edwards, Luis Furuya-Kanamori...
https://pubmed.ncbi.nlm.nih.gov/37230400Actively Recruiting
Age: 18Years +
All Genders
Healthy Volunteers
ID06919068
Colonic Capsule Endoscopy for Screening of Neoplasms in Patients With Anaerobic Bacteremia
Led by Odense University Hospital · Updated on 2025-11-18
100
Participants Needed
1
Research Sites
30 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying colorectal cancer and precancerous tumors in adults hospitalized with blood stream infections caused by anaerobic gut-associated bacteria. The study aims to find out how common cancer and precancerous tumors are in the large intestines and rectum among these patients. This observational study is led by Odense University Hospital and focuses on diagnosing these conditions after infection. Participants will be offered a colon capsule endoscopy using the PillCam Colon 2 device about 4 to 8 weeks after they are discharged from the hospital. This involves swallowing a small camera in a pill form that takes images of the colon to help detect tumors or cancerous growths. The study does not involve any treatment but focuses on screening and diagnosis. During the study, participants will undergo this colon capsule endoscopy examination and researchers will track the presence of colorectal cancer and precancerous tumors within 4 to 8 weeks after hospitalization. Participants must be able to give consent and communicate in Danish. The study monitors safety by excluding those with certain medical conditions or previous surgeries and collects data to better understand cancer prevalence in this patient group.
CONDITIONS
Brief Title
Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria
Who Can Participate
Age: 18Years +
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Older than 18 years
- Blood culture showing growth of one or more specified anaerobic gut-associated bacteria
- Able to provide oral and written informed consent
- Able to read and speak Danish
You will not qualify if you...
- Prior diagnosis of colorectal cancer
- History of gastrointestinal tract narrowing (stenosis)
- Previous treatment for inflammatory bowel disease
- Previous major surgery of the gastrointestinal tract (e.g., gastric bypass)
- Presence of colostomy
- Pacemaker or implantable cardioverter defibrillator (ICD)
- Pregnancy or breastfeeding
- Allergies to bowel preparation
- Severe kidney disease
- Infection focus in skin, soft tissue, or outside the trunk (e.g., diabetic foot ulcer)
- Tumor in colon or rectum found on imaging
- Transfer to a hospital outside the region
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - 4 to 8 weeks after hospitalization
Participants undergo colon capsule endoscopy to screen for colorectal cancer and precancerous tumors.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Odense University Hospital
Odense, Denmark, 5000
Actively Recruiting
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Research Team
C
Charlotte Nielsen Agergaard, MD
M
Mark Bremholm Ellebæk, Professor
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Published Research Related To This Trial
Bacteremia With Anaerobic Bacteria and Association With Colorectal Cancer: A Population-based Cohort Study.
Ulrik S Justesen, Stig L Nielsen, Thøger G Jensen...
https://pubmed.ncbi.nlm.nih.gov/35380653Colorectal cancer and association with anaerobic bacteraemia: A Danish nationwide population-based cohort study.
Ulrik S Justesen, Mark B Ellebæk, Niels Qvist...
https://pubmed.ncbi.nlm.nih.gov/38960102