Actively Recruiting
Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise
Led by University of Southern California · Updated on 2026-03-25
30
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The fluctuating concentrations of female sex hormones, namely estrogen and progesterone may have an effect on the ability of the tissue to withstand challenging exercise conditions, such as eccentric exercise. These sex hormones have also been purported to influence the perceived difficulty of exercise. This study aims to uncover how the different estrogen and progesterone concentrations present throughout the menstrual cycle effect perceived readiness to perform, perceptions of difficulty, and different recovery metrics.
CONDITIONS
Official Title
Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 35 years
- Body mass index (BMI) between 18.5 and 29.9
- Not taking contraception or medications affecting reproductive status
- Regular menstrual cycles
- Not pregnant
- Medically free from chronic diseases
- New to downhill running
- Weight of 110 pounds or more
- Not taking external hormones
- No known gynecological diseases affecting menstrual regularity (e.g., PCOS, endometriosis)
You will not qualify if you...
- Amenorrhea or oligomenorrhea
- Perimenopausal or menopausal status
- Recreational or professional trail or downhill runner
- Currently on any form of contraception
- Cardiac disability
- Presence of pacemaker
- Arterial disease
- Uncontrolled bleeding
- Blood clots
- Pregnant or trying to become pregnant
- Cancerous lesions
- Sensory or mental impairments
- Unstable fractures
- Weight less than 110 pounds
- Gynecological diseases affecting menstrual regularity (e.g., PCOS, endometriosis)
- Taking external hormones
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Clinical Exercise Research Center
Los Angeles, California, United States, 90033
Actively Recruiting
Research Team
T
Todd Schroeder, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
3
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