Actively Recruiting
Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women
Led by Saint Thomas Hospital, Panama · Updated on 2025-12-04
100
Participants Needed
1
Research Sites
24 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study's primary goal is to compare the base excess (BE) values-an indicator of metabolic changes-in two groups of patients at Santo Tomás Hospital: those with severe preeclampsia and healthy, pregnant individuals. Researchers will measure these values using an arterial blood gas test before delivery or surgery. This is a prospective cohort study. The researchers will analyze various blood gas parameters, including pH, lactate, and BE, and then correlate the BE values with clinical variables and negative maternal outcomes. The expected outcome is that a abnormal BE values will be linked to a greater severity of preeclampsia. If this association is confirmed, BE could serve as an additional marker for predicting the severity of the condition and may lay the groundwork for future research on diagnostic and therapeutic standards based on blood gas analysis.
CONDITIONS
Official Title
Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Gestational age between 24 and 40 weeks
- Diagnosis of severe preeclampsia for cases
- Normal blood pressure for control group
You will not qualify if you...
- Metabolic conditions such as diabetic ketoacidosis, sepsis, or renal failure
- Clinical conditions like diarrhea or vomiting that could affect results
- Recent use of bicarbonate medication
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Saint Thomas Hospital
Panama City, Provincia de Panamá, Panama
Actively Recruiting
Research Team
F
Francisco Jordan, MD
CONTACT
A
Adriana Martinz, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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