Actively Recruiting
Exercise Activity to Improve Mobility in Patients With CKD and PAD
Led by University Hospital of Ferrara · Updated on 2025-05-31
124
Participants Needed
3
Research Sites
117 weeks
Total Duration
On this page
Sponsors
U
University Hospital of Ferrara
Lead Sponsor
U
Universita di Verona
Collaborating Sponsor
AI-Summary
What this Trial Is About
People affected by chronic kidney disease and concomitant diagnosed peripheral artery disease at intermediate stages, without contraindications to exercise therapy will be invited to participate in the study. Whose providing informed consent, will be randomly assigned to one of two groups: 1. Exercise program receiving two daily 10-minute interval walking sessions at a slow increasing speed. 2. Control group: receiving usual care including optimal medical therapy and nutritional advice. Patients of both groups will be measured at baseline, after the end of the exercise program (6-month) and at follow up (12-month). Outcome measures will include walking ability by the 6-minute walking test (primary outcome) and lower limbs perfusion, body composition, quality of life, laboratory outcomes and long-term hospitalizations.
CONDITIONS
Official Title
Exercise Activity to Improve Mobility in Patients With CKD and PAD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Chronic kidney disease at KDOQI stages III or IV and peripheral artery disease at Rutherford stages I, II, or III
- Ability to walk independently
- Cognitive function sufficient to provide informed consent, with Mini Mental Status Examination score of 20 or higher
- No clinical conditions that prevent exercise therapy (e.g., unstable angina, severe heart failure NYHA class IV, anemia with hemoglobin under 10.0 g/dl)
You will not qualify if you...
- Major limb amputations
- Planned major surgery within the next 3 months
- Comorbid conditions likely to limit survival to less than 2 years
- Inability or unwillingness to follow study protocol requirements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
University Hospital of Ferrara
Ferrara, Italy, Italy, 44124
Actively Recruiting
2
Ospedale Pederzoli Peschiera del Garda
Peschiera del Garda, Italy, Italy
Actively Recruiting
3
Grande Ospedale Metropolitano Bianchi-Melacrino-Morelli
Reggio Calabria, Italy, Italy
Actively Recruiting
Research Team
F
Fabio Manfredini Prof. Fabio Manfredini, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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