Effects of Terminal Knee Extension Exercise with Audible Cues on Muscle Activity After ACL Reconstruction in Athletes Aged 18 to 35
Led by Mahidol University · Updated on 2025-12-12
40
Participants Needed
1
Research Sites
10 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying the effects of terminal knee extension TKE exercise synchronized with audible cues on muscle activity in athletes who have undergone anterior cruciate ligament ACL reconstruction. This research focuses on how adding a metronome pace during TKE exercise may improve neuromuscular control and change motor unit behavior in the vastus medialis muscle, which is important for knee stability after surgery. The study is designed to explore the immediate effects of a single TKE exercise session with or without audible cues.
Participants will be randomly assigned to one of two groups performing TKE exercise either without audible cues or with audible cues delivered via a metronome. Both interventions involve behavioral exercise targeting the knee, applied early in the rehabilitation phase to prevent knee laxity and reduce pain compared to other exercise types. The study runs from enrollment through a two-week treatment period to assess changes in muscle motor unit behavior.
During the study, participants will undergo assessments of muscle activity, including measurements of average motor unit firing rate and peak motor unit action potential in the vastus medialis muscle. These assessments occur from enrollment to the end of the two-week treatment. Researchers will monitor participants ability to perform the exercises and their neuromuscular responses, aiming to understand how sensory cues may enhance rehabilitation outcomes in athletes post-ACL reconstruction.
CONDITIONS
Brief Title
Exercise With Audible Cues on Motor Unit Behavior in Athletes With Anterior Cruciate Ligament Reconstruction
Research Team
K
Komsak Sinsurin, PT, Ph.D., DPT
S
Sakda Nitkotom, B.Sc.
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Male or female participants who received primary ACL reconstruction within 2 weeks, with or without meniscus repair
No or mild resting pain with a numeric rating scale of 3 or less
Reconstruction using autograft including hamstrings or bone-patella bone grafts
Age between 18 and 35 years
Body mass index (BMI) between 18.5 and 25 kg/m²
Tegner activity scale level 4 or higher
You will not qualify if you...
Non-weight bearing within 2 weeks after surgery as prescribed by surgeon
Hearing problems that prevent hearing the metronome or synchronizing exercises
Knee extension limitation due to joint stiffness assessed by passive knee range of motion
Unable to actively or passively bend the knee to at least 30 degrees on the operated side
History of serious injury or surgery of lower back or lower limbs such as fractures
Lower back or lower limb pain within 6 months before the study
Use of painkiller medication
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Outpatient Treatment
Duration - 2 weeks
Participants perform terminal knee extension exercises either with or without audible cues to study the effect on neuromuscular control following ACL reconstruction.
Regular visits during the 2-week exercise period
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Published Research Related To This Trial
Auditory-cued terminal knee extension enhances vastus medialis motor unit function in the early phase following ACL reconstruction: a randomized controlled trial.