Actively Recruiting
EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation
Led by Virginia Commonwealth University · Updated on 2026-03-12
50
Participants Needed
1
Research Sites
165 weeks
Total Duration
On this page
Sponsors
V
Virginia Commonwealth University
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).
CONDITIONS
Official Title
EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 6518 years
- Diagnosis of paroxysmal AF
- Left ventricular ejection fraction 6550%
- Scheduled for catheter ablation
- Able to speak, hear, and read English
- Willing and able to provide informed consent
You will not qualify if you...
- Persistent or permanent AF
- Prior ablation (catheter based or surgical) for AF
- Significant sinus node dysfunction
- Implanted pacemaker or defibrillator
- Contraindication to or inability to complete cardiovascular magnetic resonance study
- Contraindication to or inability to complete exercise testing
- Chronic kidney disease with estimated glomerular filtration rate <30 mL/min/1.73m2
- Severe left ventricular hypertrophy
- Unrelated cardiomyopathy expected to limit exercise capacity, including hypertrophic cardiomyopathy, cardiac amyloidosis, or constrictive pericarditis
- Pulmonary arterial hypertension
- Prior cardiac surgery
- Active pregnancy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Virginia Commonwealth University
Richmond, Virginia, United States, 23298
Actively Recruiting
Research Team
P
Pamela Grizzard
CONTACT
M
Melissa Sears
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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