Actively Recruiting
Exercise Cardiovascular Magnetic Resonance In Heart Failure With Preserved Ejection Fraction
Led by Mayo Clinic · Updated on 2026-04-20
400
Participants Needed
1
Research Sites
87 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to internally validate low-field Ex-CMR as a noninvasive tool for diagnosing, phenotyping, and risk stratifying HFpEF in patients with exertional dyspnea.
CONDITIONS
Official Title
Exercise Cardiovascular Magnetic Resonance In Heart Failure With Preserved Ejection Fraction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Informed consent obtained
- Participants divided into three groups: HFpEF diagnosed by cardiologist with EF ≥50%, non-cardiac dyspnea patients verified by invasive exercise testing, and healthy volunteers with no history of dyspnea or effort intolerance
You will not qualify if you...
- Contraindication for low-field CMR per MRI safety screening checklist
- Inability or unwillingness to undergo Exercise Cardiovascular Magnetic Resonance
- Cardiac implants or valves causing imaging artifacts
- Hospitalization for heart failure within the last 30 days
- Large R-R interval variation due to frequent premature ventricular contractions or non-sinus rhythms affecting data quality
- Recent myocardial infarction or unstable angina
- Planned coronary, carotid, or peripheral artery revascularization
- Other causes of dyspnea such as restrictive cardiomyopathy, infiltrative conditions (e.g., amyloidosis), hypertrophic obstructive cardiomyopathy, primary pulmonary arterial hypertension, moderate or severe COPD, right heart failure from pulmonary disease, complex congenital heart disease, severe anemia, or moderate or severe mitral or aortic valve disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
A
Annabelle Fuenffinger
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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