Actively Recruiting

Age: 18Years - 65Years
FEMALE
NCT04616300

Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery

Led by University of Toronto · Updated on 2024-12-06

50

Participants Needed

1

Research Sites

280 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will primarily identify longitudinal associations between cardiorespiratory fitness (CRF) and cognitive function pre- (baseline) to post-chemotherapy (\~3 months). This will be a prospective study of 50 BCS. We hypothesize that breast cancer patients undergoing chemotherapy who have higher levels of CRF at baseline will have significantly improved measures of attention, executive function, and memory post-chemotherapy. In addition, the exploratory aims will examine the longitudinal associations between physical activity (PA) and cognitive function from pre- to post-chemotherapy and explore the associations between inflammatory and non-inflammatory biomarkers and CRF with cognitive function.

CONDITIONS

Official Title

Exercise and Cognitive (Brain) Function in Breast Cancer Patients Getting Chemotherapy After Breast Surgery

Who Can Participate

Age: 18Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 to 65 years old
  • Histologically confirmed stage I to III breast cancer before starting chemotherapy (less than 1 cycle of adjuvant or neoadjuvant therapy)
  • No diagnosed major cognitive disorders or uncontrolled other health conditions
Not Eligible

You will not qualify if you...

  • Received neoadjuvant chemotherapy and scheduled to receive adjuvant chemotherapy
  • Scheduled to receive radiation therapy concurrently with chemotherapy

AI-Screening

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Trial Site Locations

Total: 1 location

1

Sunnybrook Health Sciences Centre-Odette Cancer Centre

Toronto, Ontario, Canada, M4N3M5

Actively Recruiting

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Research Team

L

Linda Trinh, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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