Actively Recruiting

Phase Not Applicable
Age: 18Years +
MALE
NCT05327465

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy

Led by Dana-Farber Cancer Institute · Updated on 2026-01-22

62

Participants Needed

1

Research Sites

229 weeks

Total Duration

On this page

Sponsors

D

Dana-Farber Cancer Institute

Lead Sponsor

P

Pfizer

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research is to determine whether a 16-week culturally tailored, technology-based, aerobic and resistance exercise intervention improves cardiovascular risk factors in Black men diagnosed with prostate cancer and are undergoing androgen deprivation therapy (ADT), and whether it will also improve physical fitness and function, body composition, and outcomes such as quality of life, cancer symptoms, and self-esteem. Participants in this study will be randomly assigned to one of two groups: 1) Aerobic and resistance exercise, or 2) Usual care.

CONDITIONS

Official Title

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy

Who Can Participate

Age: 18Years +
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Must be 18 years or older
  • Histologically diagnosed with localized or metastatic prostate cancer
  • Currently receiving androgen deprivation therapy for at least one month and plan to continue for at least 4 months
  • Self-identify as Black
  • Medically cleared to exercise by a physician or certified clinical exercise physiologist
  • No medical conditions that could worsen with exercise, such as bone disease at risk of fracture or uncontrolled cardiopulmonary or metabolic diseases
  • Speak English and/or Spanish
  • Currently participate in 60 minutes or less of moderate or vigorous structured exercise per week
  • Willing and able to travel to Dana-Farber Cancer Institute for data collection
  • Able to communicate and complete forms in English and/or Spanish
Not Eligible

You will not qualify if you...

  • Not receiving androgen deprivation therapy
  • Have uncontrolled cardiopulmonary or metabolic diseases that could worsen with exercise
  • Do not speak English or Spanish
  • Have a secondary diagnosis besides basal cell carcinoma
  • Participate in more than 60 minutes of moderate or vigorous structured exercise per week
  • Unable to travel to Dana-Farber Cancer Institute for study visits
  • Unable to comply with safety monitoring requirements as judged by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Dana Farber Cancer Institute

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

C

Christina Dieli-Conwright, PhD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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